Science
Mechanism of Action
This high-molecular-weight diester (1000-1700 Da) creates a breathable, occlusive barrier that effectively traps moisture by reducing transepidermal water loss (TEWL). Due to its substantial molecular size, it remains on the skin's surface to provide persistent lubrication and texture refinement without risk of systemic absorption or deeper epidermal penetration.
Research
Clinical Evidence
High confidence1.5%
Key findings
- 01 Human clinical testing at 10% concentration confirmed the ingredient is non-irritating and non-sensitizing.
- 02 Safety assessments for lip-care applications validated concentrations up to 53% as safe due to lack of dermal absorption.
- 03 Advanced skincare patent data suggests a range of 0.05% to 1.5% is effective for enhancing barrier function and skin texture.
Transparency
Dusting Analysis
While it is safe at very high levels in color cosmetics, in precision skincare, even small percentages (0.5%+) significantly contribute to barrier repair. Concentrations below 0.05% may be considered 'label dusting' if the claim is skin texture improvement.
The Formula
Formulation
Stability
Exhibits excellent stability in anhydrous (water-free) systems and remains stable within the standard physiological pH range. It may undergo hydrolysis if exposed to extreme acidity or alkalinity.
Synergies
- Lipophilic active ingredients
- Ceramides
- Squalane
Conflicts
- Strong oxidizing agents
- Formulations with pH below 3.0 or above 10.0
Safety
Safety Profile
Reaffirmed safe by the CIR in 2023. Its large molecular size ensures it does not penetrate the skin barrier, making it exceptionally safe for sensitive areas and long-term use.
Your Skin
Skin Compatibility
Our Assessment
Verdict
An expertly tolerated, high-molecular-weight emollient that provides superior barrier protection and smoothing without irritating sensitive skin.
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