Science
Mechanism of Action
This compound revitalizes weakened hair follicle cells, supplies essential nutrients, and opens potassium ion channels to stimulate regeneration. It improves hair root anchoring, inhibits collagen hardening around follicles, and may reduce DHT conversion.
Research
Clinical Evidence
High confidence1.5%
Key findings
- 01 Topical formulations at 0.5% to 2% demonstrated improvements in hair density and thickness.
- 02 A 1.5% concentration in ethanol/water supported safe use and showed sustained benefits, including reduced hair loss and improved hair texture.
- 03 Long-term studies (12-24 months) with Pyrrolidinyl Diaminopyrimidine Oxide (Aminexil) revealed significant increases in hair density, thickness, and improved hair shaft quality.
- 04 Solutions containing this ingredient decreased hair shedding and increased hair mass index over 3-6 months.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Highly soluble in water, glycols, and alcohols, it is stable at room temperature within typical cosmetic vehicles. pH is a factor influencing its stability during formulation.
Safety
Safety Profile
Regulated under EC Cosmetics Regulation Annex III/93, permitting a maximum 1.5% in hair and facial hair products. The SCCNFP deemed 1.5% safe in ethanol/water, but recommended surveillance for potential side effects in sensitive individuals.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Diaminopyrimidine Oxide is a valuable ingredient for addressing hair loss and promoting hair growth, with strong clinical support and established regulatory limits at 1.5% concentration.
Related
Similar Ingredients
Finding similar ingredients…