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DIAMINOPROPIONOYL TRIPEPTIDE-33.

Valuable CAS - / SKIN CONDITIONING

This synthetic signal peptide actively shields skin cells from UV-induced DNA damage, enhances natural repair systems, and inhibits protein carbonylation. It offers significant photoprotective benefits, effectively minimizing the visible effects of both intrinsic and extrinsic aging.

Photo-protection DNA repair Anti-aging Antioxidant

Science

Diaminopropionoyl Tripeptide-33 modulates cellular pathways involved in skin homeostasis by mimicking natural peptide sequences. It combats reactive carbon species, protects DNA from UV damage, and boosts the skin's inherent DNA repair capacity, thereby preventing premature aging.


Research

High confidence
Effective range 0.01–0.05%
Optimal

0.05%

Key findings

  1. 01 At 0.01% to 0.05%, it protects skin cells from UV-induced DNA damage, enhances DNA repair, inhibits protein carbonylation, and provides photoprotection for keratinocytes and fibroblasts.
  2. 02 A 0.5% to 5% solution containing the peptide significantly improved premature aging signs, offering photo-defensive effects on epidermal keratinocytes and fibroblasts.

Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH 4 – 7
0 7 14

Stability

Optimal stability is maintained within a pH range of 4.0 to 7.0. Store in a cool, dark place, avoiding extreme heat or environmental conditions.

Conflicts

  • Strong oxidizing agents
  • Heat

Safety

CIR Status
Not reviewed
Sensitization risk Low

This ingredient is not considered toxic, irritant, mutagenic, or sensitizing. It is also preservative-free, non-animal tested, GMO-free, and vegan.


Your Skin

No Normal
No Dry
No Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Valuable

Diaminopropionoyl Tripeptide-33 is a valuable active for comprehensive skin protection and anti-aging, demonstrating efficacy in DNA repair and photoprotection.


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