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Moumoujus

DIALLYL SULPHIDE.

Insufficient Data CAS 592-88-1 / PERFUMING

Diallyl Sulphide is an organosulfur compound derived from garlic, known for its multifaceted biological activities including antioxidant, anti-inflammatory, and chemopreventive properties. It demonstrates protective effects against environmental stressors, particularly UVB-induced skin damage.

Summary

Antioxidant Anti-inflammatory Photoprotective DNA repair support Antimicrobial

Science

Mechanism of Action

It functions by modulating cellular proliferation and inflammatory pathways, reducing markers like NF-κB and COX-2 while enhancing DNA repair mechanisms via p53 and p21/Cip1. Additionally, it boosts the skin's endogenous antioxidant defense by inducing phase II enzymes.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Moderate

No specific CIR or SCCS cosmetic safety assessment is available. While FDA-permitted as a food flavoring and fragrance ingredient, general statements suggest a potential for appreciable allergic reactions, warranting caution.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

Diallyl Sulphide shows significant promise for photoprotection and anti-inflammatory action in preclinical studies, but comprehensive human clinical trials and dedicated cosmetic safety assessments are currently lacking for precise application.

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