Science
Mechanism of Action
As an alkoxylated di-ester, DI-PPG-2 MYRETH-10 ADIPATE functions as a water-dispersible and surfactant-soluble emollient. It enhances skin slip, acts as a detangler, and provides immediate, perceptible emollience, contributing to a smooth, velvety skin feel. This 'hydroactive' ingredient aids in skin hydration by minimizing water evaporation and is particularly effective at mitigating irritation induced by surfactant-based formulations.
Research
Clinical Evidence
High confidenceN/A
Key findings
- 01 A 5% concentration demonstrated a reduction in the irritation potential of a 10% Sodium Laureth Sulfate (SLES) solution by up to 40% in in vitro models (EpiOcular™ and TransEpithelial Permeability).
- 02 In a clinical trial, concentrations from 1% to 10% effectively reduced the irritation of a 1% Sodium Lauryl Sulfate (SLS) solution to a level comparable to distilled water in 75% of female subjects during a 24-hour occlusive patch test. Notably, 100% DI-PPG-2 MYRETH-10 ADIPATE was found to be less irritating than distilled water.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
This ingredient maintains stability across a pH range of 5.0 to 7.0 and is broadly compatible with a variety of surfactants and personal care ingredients. It performs exceptionally well in clear surfactant systems and does not negatively impact foaming when used at levels up to 3%. Furthermore, it can pre-solubilize challenging materials like Benzophenone-3 at concentrations up to 20-25% and is effective for hair dyes.
Synergies
- Surfactant systems (maintains clarity, mitigates irritation)
- Ingredients requiring solubilization (e.g., Benzophenone-3, hair dyes)
Safety
Safety Profile
DI-PPG-2 MYRETH-10 ADIPATE is considered safe for cosmetic use, demonstrating low irritation potential. While the ethoxylation process in its production can generate trace amounts of 1,4-dioxane, reputable manufacturers ensure levels in finished products are below 1 ppm, complying with safety regulations. It is approved for cosmetic use in Europe, listed in the EU COSING database for its skin conditioning and emollient properties in both rinse-off and leave-on products. Typical usage levels range from 1-25%, with 1-10% being well-tolerated across various skin types, and 1-5% common in surfactant-based systems.
Your Skin
Skin Compatibility
Our Assessment
Verdict
DI-PPG-2 MYRETH-10 ADIPATE is a valuable ingredient, highly effective in providing emollience and comfort, significantly reducing irritation in surfactant-based formulations, and contributing to a superior sensory experience across all skin types.
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