Science
Mechanism of Action
Desamido Collagen penetrates deeply into the skin, where it is believed to stimulate the natural production of collagen, thereby improving elasticity and firmness. It functions as a potent humectant, efficiently drawing and retaining moisture to sustain skin hydration and suppleness. Additionally, it supports cellular renewal, offers protection against oxidative stress, and reinforces the skin's protective barrier by acting as a structural scaffold for connective tissues.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 Observed to provide skin moisturization effects comparable to well-established humectants like urea and sodium pyrrolidone carboxylate, particularly when incorporated into O/W and W/O emulsions and aqueous lotions.
- 02 Described as highly effective in skincare for improving skin structure, increasing elasticity, and delivering regenerative and firming benefits by penetrating into deeper skin layers. It also supports skin cell regeneration and provides protection against environmental stressors.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Optimal stability is achieved by storing Desamido Collagen in a cool, dry environment, protected from direct sunlight and temperatures exceeding 30°C. The deamidation process, fundamental to its formation, can influence stability; deamidation of asparagine to aspartate generally stabilizes the collagen, whereas glutamine deamidation in the Y-position may lead to destabilization.
Conflicts
- Iron-ions (especially in combination with oxygen, as this may reduce viscosity)
- Formaldehyde
Safety
Safety Profile
Desamido Collagen exhibits a favorable safety profile, generally well-tolerated without serious side effects. The Cosmetic Ingredient Review (CIR) Panel previously concluded that Hydrolyzed Collagen, its precursor, is safe for cosmetic use. Regulatory databases like COSMILE Europe list it as a skin conditioning and film-forming agent. EWG Skin Deep rates it 'LOW' for potential hazards including cancer, allergies, and reproductive toxicity. No specific SCCS opinion or FDA status for Desamido Collagen itself was found in the provided research.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Desamido Collagen is a valuable ingredient for precision skincare, offering noted benefits in skin moisturization, elasticity, and regeneration, supported by a favorable safety profile across all skin types.
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References
Sources