Science
Mechanism of Action
This extract is rich in bioactive compounds such as polysaccharides, flavonoids, sesquiterpenes, and phenols. Its polysaccharides are instrumental in enhancing skin hydration and elasticity, thereby offering moisturizing and anti-aging benefits. The combined action of its constituents also provides potent antioxidant and anti-inflammatory effects, supporting comprehensive skin rejuvenation.
Research
Clinical Evidence
Low confidenceN/A
Key findings
- 01 In vitro studies indicated that an aqueous extract of D. huoshanense at concentrations of 2-10 mg/ml could effectively inhibit the proliferation of HeLa cells, demonstrating antitumor activity.
- 02 Further in vitro research identified optimal non-cytotoxic concentrations (100-500 μg·mL−1) for gastroprotective effects in ethanol-injured GES-1 cells. Notably, lower doses (10-50 μg·mL−1) were observed to alter basal cellular viability.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
The raw material typically exhibits a pH range of 3.9-7.2. Formulators should be aware that cloudiness or precipitation may occur, potentially necessitating filtration for optimal product clarity.
Safety
Safety Profile
No specific safety assessments by CIR or SCCS have been found for Dendrobium Huoshanense Leaf/Stem Extract. The ingredient is listed for compliance under EU Cosmetics Regulation 1223/2009. Data on dermal, oral, parenteral, or inhalation toxicity for this specific extract are not available. While some Dendrobium leaf extracts have demonstrated in vitro genotoxic effects at elevated concentrations, this particular finding has not been reported for Dendrobium huoshanense Leaf/Stem Extract. In vitro studies for gastroprotective effects noted altered basal cell viability at concentrations between 10-50 μg·mL−1.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Dendrobium Huoshanense Leaf/Stem Extract is a valuable botanical offering robust hydration, antioxidant, and anti-inflammatory properties; however, precise dermal clinical efficacy data and comprehensive safety assessments specific to cosmetic use are currently limited.
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References
Sources