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DELTA-VALEROLACTONE.

Questionable CAS 542-28-9 / NOT REPORTED

Delta-Valerolactone is a cyclic ester primarily utilized as a chemical intermediate in the synthesis of polymers, particularly polyesters for biomedical applications. It lacks an established mechanism of direct action on the skin as an active ingredient.

Science

This compound primarily serves as a building block for producing polyesters, which are valued for their biocompatibility and biodegradability in drug delivery systems and tissue engineering. There is no documented mechanism outlining any direct functional impact of delta-valerolactone on skin physiology or appearance when applied topically.


Research

Insufficient-data confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

Delta-Valerolactone is not recognized as a direct active skincare ingredient, thus 'dusting' considerations are not applicable.


The Formula

Solubility
Both
Optimal pH N/A
0 7 14

Stability

Delta-Valerolactone demonstrates good thermal stability, characterized by a high boiling point and low vapor pressure. It is highly sensitive to moisture and should be stored refrigerated in tightly sealed containers. The compound is prone to acid-promoted ring-opening, which occurs more readily compared to gamma-butyrolactone.

Conflicts

  • Strong acids (due to enhanced ring-opening reactions)

Safety

CIR Status
Not reviewed
Sensitization risk Unknown

While generally noted for low systemic toxicity and classified as an FDA and EU food flavoring agent, safety data sheets indicate Delta-Valerolactone causes serious eye damage (H318 hazard statement) and carries a 'Danger' signal word. It is also moisture-sensitive, requiring careful handling to prevent degradation and potential hazards.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Questionable

Delta-Valerolactone is primarily a chemical intermediate with no identified direct skincare benefits, and its hazard profile includes a warning for serious eye damage.


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