Science
Mechanism of Action
It functions as a bFGF-related peptide that activates the growth and migration of melanocytes. By stimulating these pigment-producing cells to repopulate depigmented areas, it facilitates natural re-pigmentation and restores structural cellular balance.
Research
Clinical Evidence
High confidence0.1%
Key findings
- 01 A real-world study demonstrated that a 0.1% concentration achieved over 75% re-pigmentation in 71% of vitiligo patients over a 5-month period, with a 96.92% patient tolerability rate.
Transparency
Dusting Analysis
Given its potent biological activity as a growth factor mimetic, concentrations below 0.1% may significantly delay or reduce the efficacy of re-pigmentation results.
The Formula
Formulation
Stability
Like most peptides, it is sensitive to thermal degradation; it is ideally stored as a lyophilized powder or in stabilized aqueous solutions at low temperatures (+4°C) to maintain structural integrity.
Synergies
- Phototherapy
- Corticosteroids
Conflicts
- Strong Proteolytic Enzymes
- Extreme pH Environments
Safety
Safety Profile
Clinically proven to be well-tolerated; mild, transient side effects such as local irritation or dryness may occur but typically resolve without intervention.
Your Skin
Skin Compatibility
Our Assessment
Verdict
A highly effective, clinically-backed peptide for targeted re-pigmentation and melanocyte stimulation.
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References
Sources