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Moumoujus

DECAPEPTIDE-15.

Valuable CAS - / SKIN CONDITIONING

DECAPEPTIDE-15 is a basic fibroblast growth factor (bFGF)-related decapeptide, primarily investigated for its capacity to stimulate melanocyte growth and migration. This targeted action supports re-pigmentation processes within the skin.

Summary

Re-pigmentation Melanocyte stimulation Melanin synthesis support

Science

Mechanism of Action

As a bFGF-related decapeptide, DECAPEPTIDE-15 functions by actively stimulating the proliferation and migration of melanocytes. This mechanism directly contributes to the synthesis and distribution of melanin, thereby facilitating re-pigmentation in areas affected by melanin deficiency.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

0.1%

Key findings

  1. 01 A 0.1% solution of a bFGF-related decapeptide (referring to DECAPEPTIDE-15 in this context) demonstrated significant improvement in re-pigmentation for patients with vitiligo. A marked response (>75% re-pigmentation) was achieved by 71% of patients over an average of five months of follow-up. The treatment was well tolerated, with 96.92% of patients experiencing no adverse effects.

Transparency

Dusting Analysis

Not commonly dusted

No specific data is available to indicate that DECAPEPTIDE-15 is commonly dusted, nor to establish a dusting threshold or red flag percentage.

The Formula

Formulation

Solubility
Unknown
Optimal pH N/A
0 7 14

Stability

Specific stability data for DECAPEPTIDE-15 is currently unavailable. However, general peptide stability is known to be affected by environmental factors such as light exposure, heat treatment, pH variations, and the presence of peroxides, which can alter structure and decrease activity.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

DECAPEPTIDE-15 has not undergone specific safety assessments by major regulatory bodies such as CIR, SCCS, or FDA. While other distinct peptides like Decapeptide-12 and Decapeptide-4 are generally considered safe and well-tolerated, these findings cannot be directly extrapolated. The single clinical study evaluating 0.1% bFGF-related decapeptide reported high tolerability in 96.92% of participants.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

DECAPEPTIDE-15 is a valuable ingredient specifically for targeted re-pigmentation, having demonstrated strong clinical efficacy at 0.1% in treating vitiligo, although comprehensive data regarding its general skincare benefits, broader formulation characteristics, and regulatory safety profile remains limited.

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