Science
Mechanism of Action
Operating as a mild amphoteric surfactant, DEA-COCOAMPHODIPROPIONATE (referring to Disodium Cocoamphodipropionate) effectively interacts with both water and lipid-based impurities. This action forms micelles, enabling the removal of dirt and oil from the skin and hair upon rinsing. It additionally functions as a foam booster, contributing to a rich lather and enhancing the overall mildness and skin-feel of cosmetic formulations.
Research
Clinical Evidence
High confidenceN/A
Key findings
- 01 A cleansing cream formulated with 5% Disodium Cocoamphodipropionate exhibited non-irritating and non-sensitizing characteristics in a Human Repeated Insult Patch Test (HRIPT).
- 02 No instances of sensitization were observed in a maximization assay involving 25 subjects, who used a diluted hair product containing 0.1% Disodium Cocoamphodipropionate.
- 03 This ingredient has been employed in specialized applications, including hemorrhoid treatment formulations at 0.35% and contact lens disinfecting solutions up to 0.04%.
Transparency
Dusting Analysis
The Formula
Formulation
Safety
Safety Profile
The Expert Panel for Cosmetic Ingredient Safety (CIR) concluded that Disodium Cocoamphodipropionate is safe for cosmetic use when formulated to be non-sensitizing. This assessment was reaffirmed through reviews in 1990, 2008, and 2023. While generally well-tolerated at concentrations up to 5%, rare instances of skin sensitivity have been documented, particularly in individuals with compromised skin or when exposed to exceptionally high concentrations (e.g., 38-40% in a contact lens solution leading to worsened dermatitis in a person with eczema), or in aqueous solutions at 0.1-1% in sensitive individuals. It is crucial to note that the provided safety data specifically pertains to Disodium Cocoamphodipropionate.
Your Skin
Skin Compatibility
Our Assessment
Verdict
DEA-COCOAMPHODIPROPIONATE (based on data for Disodium Cocoamphodipropionate) is a valuable, mild amphoteric surfactant, demonstrating high safety and efficacy for cleansing and foam-boosting functions in cosmetic formulations up to 5%.
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