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DAUCUS CAROTA SATIVA ROOT CELL CULTURE LYSATE.

Valuable / SKIN CONDITIONING

This advanced ingredient, derived from red carrot root cell cultures, functions as a potent skin conditioning and rejuvenating agent. It is recognized for its significant antioxidant and anti-inflammatory properties, promoting skin repair and enhancing tolerance across all skin types.

Antioxidant Skin-Conditioning Agent Rejuvenating Repairing Anti-inflammatory Hydrating Age-defying Redness Reducer Sebum Regulator

Science

This lysate delivers its benefits through a rich composition of growth factors, peptides, and essential vitamins (A, C, E), alongside minerals. It actively promotes cellular regeneration, improving skin elasticity and visibly diminishing the appearance of aging. Its robust antioxidant capacity neutralizes reactive oxygen species (ROS) and inhibits lipoperoxidation, while its anti-inflammatory action targets silent inflammation, calms irritation, and reduces redness. The ingredient also fortifies skin's resilience against external stressors and prevents dehydration by inducing cellular protective mechanisms, including the production of polyphenolic compounds and phytosterols. Furthermore, pro-vitamin A (beta-carotene) aids in sun protection, melanin regulation, and epidermal renewal, with B vitamins and pro-vitamin A also contributing to sebaceous gland regulation.


Research

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 At a concentration of 0.1 mg/mL, this lysate demonstrated a significant protective effect against inflammation in mouse J774A.1 monocyte/macrophage cells. It also promoted the nuclear translocation of NF-κB and upregulated vascular endothelial growth factor (VEGF-A) expression in in vitro reconstructed human skin models, indicating strong antioxidant, anti-inflammatory, and skin repair capabilities.

Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH 5.5 – 5.8
0 7 14

Stability

Optimal stability and biological activity for this cell culture-derived ingredient are suggested to be within a slightly acidic pH range of 5.5 to 5.8. This range mirrors the typical growth conditions required for the stability and efficacy of cell cultures from which it is derived.


Safety

CIR Status
Not reviewed
Sensitization risk Low

Generally regarded as safe for topical application, with studies suggesting a low propensity for allergic reactions or skin irritation. However, individuals with known allergies or highly sensitive skin should exercise caution and perform a patch test. While no specific CIR or SCCS review was found for its exact INCI name, related carrot extracts are recognized as safe for cosmetic use by regulatory authorities such as the European Union when properly prepared. Its 'non-approved' status in precisionFDA for the related extract is typical for cosmetic ingredients not classified as drugs or food additives.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Valuable

This versatile ingredient is valuable for its comprehensive antioxidant, anti-inflammatory, and regenerative benefits, making it suitable for all skin types, particularly those seeking rejuvenation and enhanced resilience.


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