Science
Mechanism of Action
Daniellia Oliveri Resin Extract exerts its beneficial effects through a rich array of phytochemicals, including polyphenols, flavonoids, saponosides, alkaloids, quinone substances, polyterpenes, cardiodic heterosides, and tannins. These compounds work synergistically to combat microbial proliferation, mitigate inflammatory responses, and neutralize harmful free radicals on the skin surface. Notably, delta-cadinene, a bicyclic sesquiterpene found within the extract, has been identified as a significant antioxidant component, contributing to its protective and soothing actions.
Research
Clinical Evidence
Medium confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Safety
Safety Profile
No specific CIR, SCCS, or FDA safety assessment for Daniellia Oliveri Resin Extract for topical use is available. However, studies on aqueous extracts of Daniellia oliveri leaves demonstrated low acute oral toxicity, with an LD50 greater than 5000 mg/kg B.W. in rats, suggesting a favorable safety profile for internal consumption. Furthermore, cytotoxicity evaluations on normal human cells (MRC-5) indicated no toxicity with most active fractions. While high internal ingestion of saponins has been noted as 'not completely safe' in some contexts, this concern primarily pertains to internal use and not typical topical application.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Daniellia Oliveri Resin Extract is a valuable, multi-functional botanical ingredient, offering scientifically supported antimicrobial, antioxidant, and anti-inflammatory benefits suitable for various skin types, though further specific topical human efficacy and sensitization data would enhance its profile.
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References
Sources