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DAMNACANTHUS MAJOR EXTRACT.

Insufficient Data / HUMECTANT, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

Damnacanthus Major Extract is a botanical ingredient recognized for its antioxidant and moisturizing capabilities, with emerging potential for skin brightening. It operates through distinct cellular mechanisms to enhance skin health and appearance.

Antioxidant Humectant Skin conditioning Emollient Skin protecting

Science

This extract exhibits antioxidant effects by upregulating phospho-NFκB repressing factor in human epidermal keratinocytes. Its moisturizing properties are linked to the upregulation of phospho-extracellular signal-regulated kinase 1/2 and cAMP response element-binding protein in artificial skin models. Additionally, anthraquinone compounds found in its roots are associated with skin whitening benefits, acting as a humectant, skin conditioning, and emollient agent.


Research

Low confidence
Effective range 0.0125–0.06%
Optimal

N/A

Key findings

  1. 01 Demonstrated a distinct antioxidant effect.
  2. 02 Showed a moisturizing effect.

Transparency

Not commonly dusted

The Formula

Solubility
Both
Optimal pH N/A
0 7 14

Stability

The ethanol-extracted concentrate can be solubilized effectively in distilled water, suggesting stability within aqueous formulations.


Safety

CIR Status
Not reviewed
Max tested
0.1%
Sensitization risk Unknown

No comprehensive safety assessments by regulatory bodies such as CIR, SCCS, or FDA have been reported. A single study observed no phototoxicity at concentrations up to 0.1% (1 mg/mL).


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Insufficient Data

While initial studies indicate promising antioxidant and moisturizing benefits, the limited scope of current research, particularly on human subjects, and the lack of regulatory safety reviews necessitate further investigation for a definitive assessment.


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