Science
Mechanism of Action
The efficacy of Dalbergia latifolia Wood Extract is attributed to its complex composition, which includes biomolecules such as neoflavonoids, triterpenoids, and rotenoids like dalbergin, latifolin, and dalbergichromene. Its primary mode of action is antioxidant, achieved through the scavenging of free radicals, a benefit strongly correlated with its phenolic and flavonoid content. Latifolin contributes to its potential anti-inflammatory effects, while specific flavonoids, such as dalbergichromene, have shown in vitro antimicrobial activity against bacteria including *Staphylococcus aureus* and *Streptococcus pyogenes*. Additionally, the presence of tannins confers astringent properties.
Research
Clinical Evidence
Low confidenceN/A
Key findings
- 01 In vitro studies revealed high antioxidant activity for Dalbergia latifolia wood extract, observed within a concentration range of 250-500 µg/ml. This activity directly correlated with the extract's total phenolic content.
- 02 A methanolic extract of Dalbergia latifolia wood demonstrated potent cytotoxic activity against MCF10A ATCC breast cancer cells (IC50 of 20 µg/ml) and was non-toxic to normal human cell lines (LO2) in laboratory settings.
Transparency
Dusting Analysis
The Formula
Formulation
Safety
Safety Profile
Dalbergia latifolia wood and its sawdust have been documented to cause contact dermatitis in some individuals upon direct skin exposure. Specific cases include skin eruptions on areas like the ears and neck from wearing jewelry made from D. latifolia wood.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Despite exhibiting promising in vitro antioxidant and potential anti-inflammatory activities, the significant documented risk of contact dermatitis and an unreviewed CIR safety status make Dalbergia latifolia Wood Extract a questionable ingredient for precision skincare formulations.
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