Science
Mechanism of Action
This extract operates by actively scavenging reactive oxygen species (ROS) and reactive nitrogen species (RNS), which include DPPH, nitric oxide, superoxide anion, and hydroxyl radicals, thus mitigating oxidative stress. It also demonstrates anti-lipid peroxidation activity, further protecting cellular components. Its anti-inflammatory properties are attributed to a reduction in pro-inflammatory IL-1β levels and an increase in anti-inflammatory IL-10 cytokine production, contributing to a calmer skin state. Additionally, the extract may support skin detoxification processes, aiding in a clearer complexion.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 Hydro-alcoholic extract exhibited significant DPPH radical scavenging with an IC50 value of 1.5 µg/mL, indicating strong antioxidant potential comparable to vitamin C.
- 02 Demonstrated nitric oxide radical scavenging potential with an IC50 value of 116.0 µg/mL.
- 03 Showed superoxide anion radical scavenging capabilities with an IC50 value of 4.7 µg/mL, comparable to curcumin.
- 04 Decreased hydroxyl radical formation with an IC50 value of 27.0 µg/mL, outperforming vitamin E's IC50 of 32.5 µg/mL.
- 05 Aqueous and ethanolic extracts displayed an absence of skin-irritant effects in topical applications.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
As a botanical extract rich in phenolic compounds and flavonoids, CYTISUS SCOPARIUS BRANCH/FLOWER/LEAF EXTRACT may be susceptible to oxidative degradation. To maintain its efficacy and extend product shelf life, it is recommended to co-formulate with additional antioxidants and utilize appropriate, air-tight packaging.
Synergies
- Antioxidant co-ingredients (to enhance stability and antioxidant network)
Safety
Safety Profile
Aqueous and ethanolic extracts of Cytisus scoparius have been shown to be non-irritating at a 1% concentration in topical applications. Furthermore, a related Cytisus striatus flower extract exhibited low cytotoxicity, maintaining cell viability above 80% at concentrations up to 2000 µg/mL in human cells. While the raw plant may contain alkaloids like sparteine, which can be toxic if ingested, these concerns are generally not relevant for topical cosmetic use at common concentrations.
Your Skin
Skin Compatibility
Our Assessment
Verdict
CYTISUS SCOPARIUS BRANCH/FLOWER/LEAF EXTRACT is a valuable botanical ingredient, demonstrating significant antioxidant and anti-inflammatory properties with a low irritation risk, making it a beneficial component across various skincare formulations and suitable for all skin types.
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