Science
Mechanism of Action
This ingredient exerts its beneficial effects by modulating inflammatory pathways, specifically inhibiting the production of nitric oxide (NO) and the expression of iNOS and COX-2 enzymes. Its antioxidant capacity is attributed to a rich content of flavonoids and polyphenols, which combat oxidative stress. Furthermore, it possesses intrinsic antimicrobial and antifungal properties that contribute to overall skin health and can aid in formulation preservation.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 Stilbene dimer trans-scirpusin B and trimer cyperusphenol B, isolated from the root extract, demonstrated concentration-dependent inhibitory activity against nitric oxide production and reduced iNOS and COX-2 expression in LPS-treated murine macrophages (in vitro) at concentrations between 1-10 µM.
- 02 An ethanolic extract showed antiproliferative activity on cancer cells (glioblastoma, breast, lung) in vitro at concentrations from 12.5-50 µg/mL, while exhibiting low cytotoxicity on healthy cells at concentrations below 50 µg/mL.
- 03 Cyperus articulatus essential oil has been traditionally used for topical analgesic application when diluted in a carrier oil to a 1-2% concentration.
Transparency
Dusting Analysis
No data is available to indicate that Cyperus Articulatus Root is commonly over-formulated or 'dusted' in cosmetic products.
The Formula
Formulation
Stability
The essential oil derived from Cyperus articulatus root can enhance formulation stability by providing antifungal properties, helping to protect products against mold.
Safety
Safety Profile
Cyperus Articulatus Root is generally considered safe for topical use in cosmetic products. However, there is currently no specific safety assessment report with a determined maximum concentration available from regulatory bodies such as the Cosmetic Ingredient Review (CIR), Scientific Committee on Consumer Safety (SCCS), or FDA in the provided research.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Cyperus Articulatus Root is a valuable ingredient with demonstrated in vitro anti-inflammatory, antioxidant, and antimicrobial properties, making it a versatile addition for skin conditioning across all skin types.
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References
Sources