Science
Mechanism of Action
The extract's primary mechanism involves its component, paeonol, which actively protects against solar ultraviolet (SUV)-induced skin inflammation. This is achieved by modulating key cellular pathways, specifically targeting T-LAK cell-originated protein kinase (TOPK), p38 kinases, and JNKs. Furthermore, it inhibits the release of pro-inflammatory cytokines such as IL-6 and TNF-α within skin inflammation models. Traditionally utilized for its notable antipruritic effects in conditions like urticaria and tinea dermatosis, the extract also contains phenolic compounds that confer robust antioxidant capabilities, contributing to overall skin health and texture improvement.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Safety
Safety Profile
No specific safety assessments by CIR, SCCS, or FDA were identified in the provided research data, indicating a need for further comprehensive evaluation.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Cynanchum Paniculatum Extract is a valuable ingredient, demonstrating potent anti-inflammatory, soothing, and regenerative effects for various skin types, supported by clear mechanistic insights and traditional use.
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References
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