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Moumoujus

CYNANCHUM PANICULATUM EXTRACT.

Valuable / HUMECTANT, SKIN CONDITIONING, SKIN PROTECTING

Cynanchum Paniculatum Extract is a botanical ingredient recognized for its comprehensive skin-calming and restorative properties, particularly effective in mitigating inflammation and itch. It offers significant anti-eczema and antipruritic benefits, while also providing robust antioxidant protection and supporting the improvement of skin texture and regeneration.

Summary

anti-inflammatory soothing antioxidant anti-eczema antipruritic skin regeneration improves skin texture

Science

Mechanism of Action

The extract's primary mechanism involves its component, paeonol, which actively protects against solar ultraviolet (SUV)-induced skin inflammation. This is achieved by modulating key cellular pathways, specifically targeting T-LAK cell-originated protein kinase (TOPK), p38 kinases, and JNKs. Furthermore, it inhibits the release of pro-inflammatory cytokines such as IL-6 and TNF-α within skin inflammation models. Traditionally utilized for its notable antipruritic effects in conditions like urticaria and tinea dermatosis, the extract also contains phenolic compounds that confer robust antioxidant capabilities, contributing to overall skin health and texture improvement.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

No specific safety assessments by CIR, SCCS, or FDA were identified in the provided research data, indicating a need for further comprehensive evaluation.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
No Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Cynanchum Paniculatum Extract is a valuable ingredient, demonstrating potent anti-inflammatory, soothing, and regenerative effects for various skin types, supported by clear mechanistic insights and traditional use.

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