CYNANCHUM ATRATUM EXTRACT.

This extract functions through several precise pathways. Rich in flavonoids, glycosides, and saponins, it provides antioxidant protection against environmental stressors and free radical damage, which contributes to premature aging. Its anti-inflammatory action is mediated by a reduction in pro-inflammatory cytokines (e.g., IL-6, IL-1β, TNF-α, IL-4) and a decrease in NF-κB, phospho-IκBα, and MAP kinase expressions, effectively calming irritated and reddened skin. Furthermore, it supports skin regeneration and strengthens the skin barrier by regulating keratinocyte differentiation. For brightening, it inhibits melanin production and tyrosinase activity by modulating the cAMP cascade and MITF pathway, simultaneously boosting the skin's intrinsic antioxidant capacity.