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CYMBOPOGON MARTINI HERB EXTRACT FORMATE.

Valuable CAS 94266-45-2 / PERFUMING

A refined botanical derivative of Palmarosa grass, this extract serves as a multifunctional bioactive agent designed to harmonize the skin microbiome and manage oxidative stress. It is particularly valued in precision skincare for its ability to bridge the gap between aromatic luxury and clinical antimicrobial efficacy.

Antimicrobial Antioxidant Soothing Agent Sebum Regulator Fragrance

Science

This ingredient operates through a multi-pathway approach: it suppresses pro-inflammatory mediators like nitric oxide and TNF-α while actively stimulating IL-10, an anti-inflammatory cytokine, at concentrations as low as 5 µg/mL. Furthermore, it exhibits potent antimicrobial action by disrupting the plasma membranes of pathogens, including Cutibacterium acnes, and offers high-level antioxidant protection with a 92.7% nitric oxide scavenging rate.


Research

Medium confidence
Effective range 5–500%
Optimal

N/A

Key findings

  1. 01 Demonstrated minimum inhibitory concentrations (MIC) against skin-relevant Gram-positive bacteria between 125-300 µg/mL.
  2. 02 Achieved 92.7% nitric oxide scavenging and 74% metal chelating activity in antioxidant assays.
  3. 03 Stimulated anti-inflammatory IL-10 production in human monocytes at a noncytotoxic threshold of 5 µg/mL.

Transparency

Commonly dusted
Min. effective
0.5%
Red flag below
0.1%

Because this extract also functions as a fragrance component, it is frequently included at very low percentages (below 0.1%) for its scent profile. To achieve the documented antimicrobial and anti-inflammatory benefits, concentrations must align with the higher microgram-per-milliliter ranges seen in clinical data.


The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Highly volatile and susceptible to photodegradation; ideally formulated within inclusion complexes like β-cyclodextrin or stabilized with corn starch to preserve phenolic integrity.

Synergies

  • Tween 80 (for micellar solubilization)
  • Corn starch (phenolic stabilization)

Conflicts

  • Lactose monohydrate

Safety

CIR Status
Not reviewed
Sensitization risk Moderate

Recognized by the European Commission as a potential skin allergen. While it carries a low acute toxicity profile (LD50 > 5000 mg/kg), its status as an established contact allergen requires patch testing for reactive skin types.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Moderate
Comedogenicity Low

Our Assessment

Valuable

A high-performance botanical that excels at balancing oily and inflamed skin, though its potential for sensitization necessitates precise formulation.


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