Science
Mechanism of Action
On skin, Cyclohexanone primarily functions as a potent solvent, leading to non-immune-mediated adverse effects. These include direct primary irritation, corrosive actions, potential alterations in skin pigmentation, and a significant compromise or disruption of the skin's natural barrier integrity.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
Cyclohexanone is an industrial solvent and is explicitly deemed unsuitable for any cosmetic or consumer application due to its inherent hazards.
The Formula
Formulation
Stability
Cyclohexanone generally remains stable under typical conditions but may develop a pale yellow tint over time due to oxidation. It is reactive with oxidizing agents. Optimal storage involves light-impermeable containers, ideally under an inert gas like nitrogen.
Conflicts
- oxidants (e.g., nitric acid)
- synthetic materials (e.g., PVC, polystyrol, rubber)
- grease
- resins
- lacquer
Safety
Safety Profile
Evaluated as highly hazardous, Cyclohexanone has a maximum permitted concentration of 0% in skincare products. The National Institute for Occupational Safety and Health (NIOSH) assigns a SK: DIR (COR) notation, signifying direct corrosive effects on the skin. It is explicitly deemed unsuitable for consumer use due to flammability and severe health risks, including extreme irritation, potential organ damage upon contact, and confirmed skin barrier disruption. It is not listed as an approved ingredient on INCI for cosmetics.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Cyclohexanone is a highly hazardous industrial solvent explicitly unsuitable for cosmetic or consumer use due to its extreme irritancy, corrosive properties, and potential for severe health impacts on the skin and body.
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References
Sources