Science
Mechanism of Action
Cutibacterium granulosum ferment extract filtrate works through multiple pathways. As a skin conditioning agent and emollient, it helps to maintain and soften the skin, contributing to barrier integrity. Its deeper action involves the byproducts of fermentation, such as enzymes and peptides. Notably, research indicates that the parent bacterium, Cutibacterium granulosum, secretes an extracellular DNase, BmdE, which possesses the ability to degrade the biofilm matrix of Cutibacterium acnes. This mechanism suggests a role in inter-species competition within the skin microbiome, which can disrupt C. acnes biofilms and potentially contribute to anti-acne effects.
Research
Clinical Evidence
Medium confidenceN/A
Transparency
Dusting Analysis
No data available to suggest this ingredient is commonly 'dusted' at ineffective concentrations.
The Formula
Formulation
Safety
Safety Profile
While not specifically reviewed by the CIR Expert Panel, similar 'ferment extract filtrate' ingredients (e.g., Lactobacillus-derived) are considered safe. SkinSAFE categorizes this ingredient as 'Irritant Free', 'Teen SAFE', 'Lip SAFE', 'Baby SAFE', and 'Eyelid SAFE', indicating a generally favorable safety profile free from common irritants and allergens.
Your Skin
Skin Compatibility
Our Assessment
Verdict
This ingredient is valuable for its dual benefits as a skin conditioner and its demonstrated efficacy in improving acne-prone skin by modulating the skin's microbiota, particularly by disrupting C. acnes biofilms.
Related
Similar Ingredients
Finding similar ingredients…
References
Sources