Science
Mechanism of Action
This extract functions as a powerful antioxidant by enhancing the skin's intrinsic antioxidant enzyme activities, thereby neutralizing oxidative stress. Its anti-inflammatory action is precisely achieved by inhibiting the production of nitric oxide (NO), TNF-α, and IL-1β, alongside blocking the activation of NF-κB, which are central to inflammatory responses. For sensitive or atopic-prone skin, it can also mitigate inflammatory mediators such as mTARC, histamine, and IgE. Furthermore, it contributes to skin brightening by inhibiting tyrosinase activity and offers anti-aging effects by impeding elastase, potentially supporting the skin's own collagen production, enhancing firmness and elasticity, and aiding in barrier repair and protection.
Research
Clinical Evidence
Medium confidenceN/A
Transparency
Dusting Analysis
Specific data on dusting or common underdosing percentages for Cudrania Tricuspidata Fruit Extract were not available in the provided research.
The Formula
Formulation
Stability
Formulations containing Cudrania tricuspidata root extract demonstrated stability at 25°C for 21 days. However, noticeable deviations in viscosity and particle size at 47°C suggest potential temperature sensitivity that formulators should consider for long-term product integrity.
Safety
Safety Profile
In vitro studies indicated no cell toxicity up to 1,000 μg/mL in an MTT test. It is generally regarded as non-irritating, consistent with a low irritancy rating from INCIDecoder.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Cudrania Tricuspidata Fruit Extract is a valuable ingredient, offering a broad spectrum of benefits from antioxidant and anti-inflammatory actions to anti-aging and brightening effects, with a favorable safety profile across all skin types.
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References
Sources