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CUCURBITA PEPO SEED EXTRACT.

Valuable CAS 89998-03-8 / SKIN CONDITIONING

Cucurbita Pepo Seed Extract is a multifaceted botanical ingredient renowned for its comprehensive skin benefits. It actively supports skin structure by boosting collagen, offers robust antioxidant protection, and reduces inflammation. This extract also promotes a hydrated, smoother, and more even complexion across various skin types.

Summary

Antioxidant Soothing Skin-softening Collagen boosting Anti-inflammatory Hydrating Exfoliating Promotes elasticity and firmness Photoprotective

Science

Mechanism of Action

This extract operates through several biological pathways to enhance skin health. It significantly stimulates the production of collagen and fibrillin, while concurrently inhibiting enzymes responsible for their degradation, thereby strengthening the skin's structural integrity. As a potent antioxidant, it neutralizes free radicals, mitigating oxidative stress and UV-induced damage that contribute to premature aging. Its anti-inflammatory capabilities are evidenced by its ability to downregulate inflammatory cytokines, providing relief for irritated skin and conditions such as psoriasis and dermatitis. Furthermore, the extract aids in hydration by forming a protective barrier that minimizes transepidermal water loss. It also contains natural alpha hydroxy acids, fruit enzymes, and vitamins A and C, which collectively contribute to gentle exfoliation, revealing a brighter, softer skin surface and improving overall elasticity and firmness.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

4%

Key findings

  1. 01 Demonstrated an ability to visibly smooth fine lines and wrinkles, while enhancing skin vitality and tone. It also shows promise in the prevention and attenuation of stretch mark appearance.
  2. 02 Significantly increased collagen synthesis and offered notable photoprotection for the skin.
  3. 03 Found to be non-cytotoxic to human keratinocytes and deemed non-irritant for topical application.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH 3 – 8
0 7 14

Stability

Components derived from the seed, such as pumpkin seed protein isolate (PSPI) and its hydrolysate (PSPH), exhibit stability across a pH range of 3 to 8. It's important to note that Cucurbita Pepo Seed Oil is distinct and insoluble in water.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

Formal safety assessments for 'Cucurbita Pepo Seed Extract' by regulatory bodies like CIR, SCCS, or FDA are currently unavailable. While in vitro studies on peel extracts indicate non-irritancy at concentrations up to 1000 µg/mL, and Cucurbita Pepo Seed Oil is generally considered safe for topical use on most skin types, including sensitive skin, thorough safety testing is advised for specific formulations due to the inherent potential for irritation or sensitization with natural extracts.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Cucurbita Pepo Seed Extract is a valuable ingredient, offering proven benefits in collagen synthesis, antioxidant defense, and skin soothing, making it suitable for a broad range of skin concerns and types.

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