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Moumoujus

CRYPTOMERIA JAPONICA STEM OIL.

Valuable / FRAGRANCE

Cryptomeria Japonica Stem Oil, derived from the Japanese cedar, is a potent essential oil recognized for its multi-functional benefits in precision skincare. It offers significant antimicrobial, anti-inflammatory, and antioxidant properties, making it particularly beneficial for maintaining balanced and healthy skin and addressing specific concerns.

Summary

Antimicrobial Antibacterial Antifungal Anti-inflammatory Antioxidant Acne Treatment Support Skin Soothing Skin Barrier Support

Science

Mechanism of Action

Cryptomeria Japonica Stem Oil acts through a multi-pronged mechanism to improve skin health. It demonstrates robust antibacterial activity against acne-causing bacteria like Propionibacterium acnes and Staphylococcus epidermidis, alongside potent antifungal action against dermatophytic fungi. Its anti-inflammatory effects stem from the inhibition of key inflammatory mediators such as nitric oxide, prostaglandin E2, tumor necrosis factor-alpha, interleukin-1beta, and interleukin-6. Furthermore, it provides antioxidant protection by scavenging free radicals and preventing lipid oxidation, collectively supporting skin balance, barrier integrity, and overall healing.

Research

Clinical Evidence

Medium confidence
Effective range 0.01–1%
Optimal

N/A

Key findings

  1. 01 Demonstrated highly effective antifungal activity against dermatophytic fungi. A specific fraction (D) of C. japonica essential oil was effective at concentrations exceeding 0.01% (100 ppm).
  2. 02 Exhibited excellent antibacterial activities against Propionibacterium acnes and Staphylococcus epidermidis, key bacteria implicated in acne. Minimal inhibitory concentrations (MIC) ranged from 0.016% to 1.0% (0.16 to 10.0 microl/ml) for C. japonica essential oil.
  3. 03 Showcased concentration-dependent antioxidant activities, measured by DPPH, ABTS, and BCBA assays, with EC50 values indicating significant free radical scavenging from concentrations as low as 0.026% (260 µg/mL).

Transparency

Dusting Analysis

Not commonly dusted

Insufficient data to determine if Cryptomeria Japonica Stem Oil is commonly dusted or to establish specific dusting thresholds.

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

As an essential oil, it is advisable to protect Cryptomeria Japonica Stem Oil from direct heat and sunlight exposure to preserve its stability and efficacy.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

No specific review by CIR, SCCS, or FDA is available for Cryptomeria Japonica Stem Oil. General Cryptomeria japonica essential oil is suggested for aromatherapy applications. Acute toxicity studies on leaf essential oil indicated low mortality (0-38%) at concentrations of 100–180 μg·mL−1, suggesting low acute toxicity. However, specific skin sensitization data for this ingredient remains undetermined for direct topical application.

Your Skin

Skin Compatibility

Yes Normal
No Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Cryptomeria Japonica Stem Oil is a valuable ingredient due to its proven antimicrobial, anti-inflammatory, and antioxidant capabilities, making it highly beneficial for addressing concerns such as acne, irritation, and oxidative stress.

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