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CRYPTOMERIA JAPONICA LEAF EXTRACT.

Valuable CAS 91771-60-7 / HUMECTANT

Derived from the Japanese Cedar, this botanical powerhouse serves as a multi-functional skin stabilizer, combining potent antibacterial properties with a robust antioxidant profile. It is engineered to soothe reactive skin while simultaneously targeting the microbial imbalances associated with acne-prone complexions.

antioxidant soothing antibacterial skin conditioning anti-inflammatory

Science

The extract utilizes high concentrations of polyphenols to neutralize oxidative stress and inhibit the production of pro-inflammatory cytokines and nitric oxide. On the skin's surface, it acts as a natural antimicrobial agent, disrupting the proliferation of P. acnes and S. epidermidis while reinforcing the moisture barrier to prevent trans-epidermal water loss.


Research

Medium confidence
Effective range 0.16–40%
Optimal

N/A

Key findings

  1. 01 Demonstrated significant inhibition of Propionibacterium acnes and Staphylococcus epidermidis at MIC levels of 0.16-10.0 microl/ml.
  2. 02 Identified melanin biosynthesis-inhibitory activity in melanoma cells at concentrations between 10-40 µg/mL.
  3. 03 Showed dose-dependent reduction in pro-inflammatory markers, indicating strong anti-inflammatory potential.

Transparency

Commonly dusted
Min. effective
0.1%
Red flag below
0.05%

Due to its efficacy at low MIC levels, many brands include this extract at very low 'label-claim' percentages. For targeted anti-acne or soothing benefits, concentrations should ideally align with levels that mimic clinical MIC values.


The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

The extract contains volatile components and polyphenols; stable when formulated in water-based systems, though oxidation protection is recommended.

Synergies

  • Niacinamide
  • Hyaluronic Acid
  • Salicylic Acid

Safety

CIR Status
Not reviewed
Pregnancy
Safe
Sensitization risk Low

Rated as low risk by EWG across major safety categories. While generally well-tolerated, the presence of essential oil fractions suggests a patch test for those with extreme botanical sensitivities.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Valuable

An excellent botanical choice for balancing oily and reactive skin types through its dual antibacterial and anti-inflammatory action.


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