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CRYPTOMERIA JAPONICA BUD EXTRACT.

Valuable CAS 91771-60-7 / SKIN CONDITIONING, SKIN PROTECTING

Cryptomeria Japonica Bud Extract, derived from Japanese Cedar buds, is a potent skincare ingredient engineered to enhance skin barrier integrity and promote cellular renewal. It precisely targets key biological pathways to strengthen the skin, improve hydration, and refine texture, resulting in a visibly smoother and more resilient complexion.

Summary

skin conditioning skin protecting barrier strengthening cell turnover enhancement moisture retention skin elasticity epidermal renewal

Science

Mechanism of Action

This extract functions as a sophisticated skin conditioning and protecting agent, working at a cellular level to optimize skin health. It actively boosts cellular metabolism, enhances elasticity, and stimulates epidermal renewal for a natural lifting and smoothing effect. Specifically, it increases KLK-5 enzyme activity by +50% to facilitate healthy skin cell turnover, elevates Ceramide synthase 3 (CerS3) mRNA by +25% to fortify the skin's lipid barrier, and boosts Involucrin by +87% and Filaggrin by +38% to improve overall skin structure and moisture retention. Furthermore, it enhances keratinocyte proliferation (indicated by a +67% increase in KI-67) and supports natural moisturizing factor production by increasing caspase-14 enzyme activity by +67%.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

1%

Key findings

  1. 01 A 1% concentration demonstrated significant improvements in skin barrier function and hydration markers. It increased KLK-5 enzyme activity by +50%, Ceramide synthase 3 (CerS3) mRNA by +25%, Involucrin by +87%, Filaggrin by +38%, KI-67 by +67%, and caspase-14 enzyme by +67%. These biochemical shifts collectively indicate enhanced skin cell turnover, a strengthened skin barrier, improved cell proliferation, and superior moisture retention capabilities.

Transparency

Dusting Analysis

Not commonly dusted

There is no information to suggest that Cryptomeria Japonica Bud Extract is commonly dusted or used at ineffective concentrations in formulations.

The Formula

Formulation

Solubility
Water
Optimal pH 3.5 – 6.5
0 7 14

Stability

This extract maintains optimal stability within a pH range of 3.5 to 6.5. To preserve its efficacy, avoid exposure to temperatures exceeding 40°C during both mixing and storage processes.

Safety

Safety Profile

CIR Status
Not reviewed
Pregnancy
Caution
Sensitization risk Low

Generally considered safe for topical cosmetic use. While potential adverse reactions such as skin irritation or redness are infrequent, a preliminary patch test is recommended before widespread application. Due to a lack of specific data regarding topical use during pregnancy and breastfeeding, individuals in these categories should consult a healthcare professional prior to use.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Cryptomeria Japonica Bud Extract is a valuable active ingredient, demonstrating precise biochemical enhancements for robust skin barrier function, optimal hydration, and accelerated cellular renewal across all skin types.

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