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Moumoujus

CROCUS SATIVUS STIGMA EXTRACT.

Valuable CAS 84604-17-1

Crocus Sativus Stigma Extract, derived from saffron, is a potent botanical ingredient recognized for its multifaceted benefits in skincare. It effectively brightens skin, reduces inflammation, and offers robust antioxidant protection, promoting an even tone and overall skin health.

Summary

antioxidant skin conditioning anti-inflammatory brightening UV protection wound healing

Science

Mechanism of Action

This extract operates as a powerful antioxidant, mitigating oxidative stress and neutralizing free radicals, with its active compound crocin providing protection against UV radiation. Its anti-inflammatory properties soothe skin, diminishing redness and irritation. Furthermore, it brightens the complexion by inhibiting tyrosinase activity, which reduces melanin formation and lessens the appearance of dark spots. The extract also supports skin conditioning, rejuvenation, and repair, contributing to improved elasticity and smoother skin texture, and promoting skin cell growth for wound healing.

Research

Clinical Evidence

Medium confidence
Effective range 3–3%
Optimal

3%

Key findings

  1. 01 A cream containing 3% Crocus sativus extract demonstrated significant depigmentation and anti-erythemic effects on human skin over an 8-week period.
  2. 02 Clinical investigations confirmed saffron's superiority over placebo in promoting skin health and reducing pruritus.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH 5 – 7
0 7 14

Stability

Saffron solutions, specifically those containing crocin, exhibit notable stability across alkaline and acidic conditions due to crocin's pKa, with an optimal pH range for the extract identified between 5.0 and 7.0.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

Generally regarded as safe for topical cosmetic use, displaying low toxicity and minimal sensitivity or irritation risks, even for sensitive skin. However, potential for individual reactions such as irritation or redness exists, warranting a patch test. Data regarding its topical safety during pregnancy and breastfeeding is insufficient, necessitating professional medical advice for these groups. Note that high oral concentrations have shown toxicity in animal studies (LD50 20.7 g/kg).

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Crocus Sativus Stigma Extract is a valuable ingredient, leveraging its potent antioxidant, anti-inflammatory, and brightening properties to significantly enhance skin health, tone, and resilience across various skin types.

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