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Moumoujus

CROCUS SATIVUS LEAF CELL CULTURE EXTRACT.

Valuable CAS 84604-17-1 / SKIN PROTECTING

CROCUS SATIVUS LEAF CELL CULTURE EXTRACT is an advanced botanical derivative engineered to provide comprehensive skin protection. Rich in potent antioxidants and anti-inflammatory compounds, it precisely shields the skin from environmental aggressors, mitigates oxidative damage, and reduces irritation, promoting a resilient and healthy complexion.

Summary

skin protecting antioxidant anti-inflammatory anti-aging soothing

Science

Mechanism of Action

This extract functions primarily as a skin protecting agent through its robust antioxidant and anti-inflammatory properties. Its efficacy stems from a rich profile of polyphenols, including flavonoids and anthocyanins, which actively neutralize free radicals induced by stressors like hydrogen peroxide and UVA radiation. It also demonstrates an ability to reduce cellular damage (cytotoxicity) caused by UVB exposure and irritants such as sodium dodecyl sulphate. Furthermore, certain *Crocus sativus* extracts exhibit inhibitory effects on enzymes like hyaluronidase, tyrosinase, and xanthine oxidase, suggesting additional benefits in maintaining skin integrity, promoting even tone, and reducing oxidative processes.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

0.003%

Transparency

Dusting Analysis

Not commonly dusted

Data specific to dusting practices for this ingredient is not available within the provided research.

The Formula

Formulation

Solubility
Both
Optimal pH ≥5
0 7 14

Stability

Optimal stability for major crocetin esters and coloring strength in saffron aqueous extracts is observed at pH levels ≥5.0. While compounds like kaempferol show stability across a broad pH range, quercetin may necessitate an acidic environment to prevent oxidation. Effective extraction of active phenolic compounds, including flavonoids and anthocyanins, from *Crocus sativus* leaves is optimally achieved using hydroalcoholic solutions (e.g., 70% ethanol or 50:50% v/v ethanol/water).

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

The FDA status for CROCUS SATIVUS LEAF CELL CULTURE EXTRACT is 'None found', and specific dermal, oral, or inhalation toxicity data are not determined for this ingredient. However, related ingredient Crocus Sativus Flower Extract is widely considered safe, non-toxic, and non-sensitizing, even for sensitive skin. All cosmetic ingredients in the EU adhere to stringent safety regulations.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

CROCUS SATIVUS LEAF CELL CULTURE EXTRACT is a valuable ingredient, offering broad-spectrum skin protection, potent antioxidant benefits, and anti-inflammatory action suitable for all skin types, including sensitive.

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