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Crocus Sativus Callus Extract

CROCUS SATIVUS CALLUS EXTRACT is a botanical ingredient derived from the callus culture of the saffron plant, offering potent antioxidant and skin conditioning benefits. It is engineered to protect the skin from environmental stressors while enhancing its overall health and appearance.

Directory entry · Individual source review pending

This profile is awaiting an individual source review. Treat its ratings, dose estimates and compatibility labels as provisional; they are not medical advice or proof of a finished product’s effects.

Antioxidant Skin conditioning Hair conditioning

Science

This extract primarily functions as a robust antioxidant, actively neutralizing free radicals and mitigating oxidative stress, which are key contributors to premature skin aging and damage. Its efficacy is attributed to a rich composition of active compounds, including polyphenols, flavonoids (such as kaempferol, quercetin, and anthocyanins), and carotenoids (like crocins). These compounds collectively scavenge reactive oxygen species, chelate transition metals to prevent the damaging Fenton reaction, and potentially modulate the activity of cellular antioxidant enzymes.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH 5 – 7
0 7 14

Stability

Optimal formulation stability is likely achieved within a pH range of 5.0 to 7.0. While many flavonoids like kaempferol demonstrate stability across a wide pH spectrum, other active compounds such as quercetin may require slightly more acidic conditions to prevent oxidation and maintain their efficacy.


Safety

CIR Status
Not reviewed
Sensitization risk Low

Specific safety assessments by regulatory bodies such as CIR, SCCS, or FDA are not readily available for CROCUS SATIVUS CALLUS EXTRACT. However, the broader Crocus Sativus extract is generally recognized as safe and well-tolerated, with a low risk of skin sensitivity or irritation. It is rated as non-comedogenic (0 on a scale of 0 to 5), indicating it is highly unlikely to clog pores. As a precautionary measure, patch tests are recommended before widespread use, particularly for individuals with highly reactive skin.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

CROCUS SATIVUS CALLUS EXTRACT is a valuable botanical active, offering significant antioxidant protection and skin conditioning benefits with an excellent safety profile, making it a well-tolerated addition to diverse skincare formulations.


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