Science
Mechanism of Action
It operates as a multi-modal biological shield by neutralizing reactive oxygen species (ROS) and inhibiting the expression of matrix metalloproteinases (MMPs), the enzymes responsible for collagen degradation. Simultaneously, it upregulates type I procollagen synthesis and enhances the skin's microcirculation, promoting a more resilient and hydrated dermal environment.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 In vivo trials demonstrated a 34% increase in skin moisture levels and significant reductions in wrinkle scores over a 6-month period.
- 02 Inhibition of UVB-induced epidermal thickening through the modulation of chlorogenic acid and procyanidin B2 pathways.
- 03 Significant skin hydration improvements observed in subjects with specific TERT gene polymorphisms.
Transparency
Dusting Analysis
Due to its complex extract profile (including epicatechin and procyanidin B2), it is often included at 'label claim' levels (below 0.1%) where it offers negligible biological activity. Effective formulas require higher concentrations to achieve the documented 34% moisture increase.
The Formula
Formulation
Stability
Highly sensitive to pH; phenolic stability is maximized in acidic environments (pH 3.0-4.5). Exposure to moist, non-acidic conditions can accelerate procyanidin decomposition.
Synergies
- Vitamin C
- Hyaluronic Acid
- Ferulic Acid
Conflicts
- High-moisture carbohydrate matrices
- Alkaline formulations
Safety
Safety Profile
Generally well-tolerated with an excellent safety profile, though individuals with known Rosaceae allergies should exercise caution.
Your Skin
Skin Compatibility
Our Assessment
Verdict
A high-performance botanical for age-prevention and hydration, provided it is stabilized in low-pH formulations.
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