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COTTONSEED GLYCERIDE.

Valuable CAS 8029-44-5 / SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SURFACTANT - CLEANSING, SURFACTANT - EMULSIFYING

A sophisticated lipid-derived emollient that balances moisture retention with skin barrier support. It serves as a multifunctional ingredient that stabilizes formulas while providing essential fatty acids to the epidermal layer.

Skin Conditioning Emollient Emulsifying Agent Barrier Support

Science

Cottonseed Glyceride functions as a biomimetic skin conditioner that forms a protective, non-occlusive film to lock in hydration. Rich in linoleic acid and Vitamin E, it supports the skin's lipid barrier and enhances the penetration of other active ingredients by modifying the permeability of the stratum corneum.


Research

Medium confidence
Effective range 1–5%
Optimal

3%

Key findings

  1. 01 Established efficacy and safety standards within the 1-5% concentration range for cosmetic topical applications.

Transparency

Not commonly dusted
Min. effective
1%
Red flag below
0.5%

Because it often doubles as a functional emulsifier, it is rarely 'dusted' at negligible amounts; however, to achieve therapeutic emollient benefits, concentrations should meet the 1% threshold.


The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Highly dependent on the refinement process to ensure the removal of gossypol and heavy metals. Refined versions exhibit superior oxidative stability and extended shelf life in anhydrous or emulsion systems.

Synergies

  • Vitamin E
  • Linoleic Acid
  • Antioxidants

Safety

CIR Status
Safe as used with restrictions
Max tested
5%
Pregnancy
Safe
Sensitization risk Low

Safety is contingent on the purity of the source; must be free from detectable gossypol, pesticides, and cyclopropenoid fatty acids.


Your Skin

Yes Normal
Yes Dry
No Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Valuable

A reliable emollient and emulsifier that provides essential fatty acids to support barrier health in dry and sensitive skin profiles.


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