Science
Mechanism of Action
This extract operates through several key pathways. It is rich in potent antioxidants, including ergothioneine and selenium, which effectively neutralize free radicals and mitigate oxidative stress. The presence of kojic acid enables targeted inhibition of melanin synthesis, leading to a reduction in dark spots, acne scars, and overall skin brightening. High concentrations of polysaccharides and lentinan ensure deep hydration, enhance moisture retention, and fortify the skin's natural barrier, visibly improving skin texture and reducing the appearance of fine lines. Furthermore, its zinc and amino acid content supports collagen integrity and formation, while its anti-inflammatory properties soothe irritation, making it beneficial for various sensitive skin conditions.
Research
Clinical Evidence
Medium confidence2-5%
Key findings
- 01 Optimal for anti-aging and brightening results in cosmetic formulations.
- 02 Increased cell viability by 60% against H2O2-induced cytotoxicity in vitro.
- 03 Reduced pigmentation through tyrosinase inhibition in zebrafish embryos, with 100 μg/mL reducing pigmentation by almost 1/3, and 300 μg/mL showing stronger reduction.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Corthellus Shiitake Extract is a water-soluble ingredient stable within a pH range of 3.9 to 7.2. Its efficacy can be further enhanced when formulated alongside ingredients such as Vitamin C or Niacinamide.
Synergies
- Vitamin C
- Niacinamide
Safety
Safety Profile
Although Corthellus Shiitake Extract has not undergone specific review by the Cosmetic Ingredient Review (CIR) or SCCS, it is recognized as cosmetically compliant under EU regulations. It holds a low hazard rating of 1 out of 10 from EWG and is classified as 'Irritant Free' by SkinSAFE, indicating a very low risk of irritation or sensitization in topical applications. While large medicinal doses of general shiitake can lead to systemic issues, these concerns are not relevant for typical cosmetic concentrations.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Corthellus Shiitake Extract is a valuable, multi-functional ingredient providing comprehensive benefits from antioxidant protection and brightening to hydration and anti-aging, suitable for various skin types with a low risk of irritation.
Related
Similar Ingredients
Finding similar ingredients…