Science
Mechanism of Action
This extract functions as a robust antioxidant, actively neutralizing free radicals to shield skin from environmental oxidative damage, thereby addressing concerns like fine lines and wrinkles. Its anti-inflammatory capabilities stem from reducing key chemokine secretions (eotaxin-3/CCL26, TARC/CCL17) and inhibiting mRNA expression of macrophage-derived chemokine (MDC/CCL22). It further mitigates inflammation by suppressing nitric oxide production and the phosphorylation of IKKα, IKKβ, IκBα, and NF-κB, alongside reducing iNOS and COX-2 expression, which helps alleviate sensitivity, redness, and itching. The extract also facilitates natural exfoliation by assisting in the shedding of dead skin cells. For anti-aging, it inhibits elastase activity and decreases MMP-1 expression in UVB-exposed skin, guarding against photoaging and potentially stimulating collagen synthesis. Skin barrier integrity is improved through the upregulation of filaggrin, leading to enhanced moisture retention. Additionally, Cornus Walteri Extract contributes to skin brightening by blocking tyrosinase and reducing melanin synthesis, which may diminish spots and freckles. Its antibacterial properties help inhibit bacterial growth, making it beneficial for managing issues such as facial acne.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
The stability of Cornus Walteri Extract's active compounds, such as phenolic compounds and anthocyanins, may be compromised by high temperatures. Their stability can also vary with pH.
Conflicts
- Iridoid glycosides, which may be present in Cornus extracts, have the potential to react with amino acids, possibly resulting in the formation of undesirable colored complexes in certain formulations.
Safety
Safety Profile
No official safety assessments from CIR, SCCS, or FDA were identified for Cornus Walteri Extract. In vitro studies on reconstructed human skin and normal skin cells indicated no cytotoxicity. Other dogwood extracts have demonstrated a capacity to reduce skin irritation. General acute toxicity data (oral, dermal, inhalation) and GHS hazard statements were unavailable.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Cornus Walteri Extract is a valuable botanical ingredient offering a broad spectrum of benefits, including significant antioxidant, anti-inflammatory, and anti-aging properties, making it suitable for diverse skincare formulations.
Related
Similar Ingredients
Finding similar ingredients…
Keep exploring
From ingredients to everyday care.
Sensitive skin ↗
Start with comfort, product choices and the questions to ask.
Barrier support ↗
Understand moisture, lipids and the limits of ingredient claims.
Ingredient names help you read a label. They do not establish how a finished product will perform. Explore The Garden.