Get a Free 5ml Mini Now Free 5ml Mini With Every Order of The Mantle
Moumoujus

CORIDOTHYMUS CAPITATUS OIL.

Optional CAS 90131-59-2 / FLAVOURING

Coridothymus Capitatus Oil is a potent essential oil, rich in carvacrol, recognized for its diverse biological activities. It offers significant antioxidant, antimicrobial, and anti-inflammatory properties, making it a compelling ingredient for targeted skincare applications.

Summary

Antioxidant Antimicrobial Antibacterial Antifungal Anti-inflammatory Antibiofilm Antiviral Perfuming

Science

Mechanism of Action

The efficacy of Coridothymus Capitatus Oil primarily stems from its phenolic compounds, notably carvacrol. It exerts antibacterial action by disrupting bacterial cell membranes and interfering with essential enzymatic processes. Additionally, it exhibits antibiofilm properties by inhibiting bacterial attachment and modifying the extracellular polymeric matrix. Its antioxidant effects are attributed to its ability to scavenge and stabilize free radicals, while also interfering with early stages of viral replication and possessing anti-inflammatory benefits.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 At a concentration of 1% v/v, the oil effectively inhibited new biofilm formation and reduced mature biofilms of *Pseudomonas aeruginosa* clinical isolates.
  2. 02 It demonstrated significant inhibitory effects on the replication of Simplexvirus humanalpha1 (HSV-1) at an IC50 of 47 μg/mL.
  3. 03 The oil also exhibited significant inhibitory effects on the replication of Simplexvirus humanalpha2 (HSV-2) at an IC50 of 40 μg/mL.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

As an essential oil, Coridothymus Capitatus Oil is prone to oxidation and may require the inclusion of stabilizers for optimal performance. Its major component, thymol, exhibits low water solubility and high volatility, suggesting that advanced formulation techniques like encapsulation could enhance stability and water dispersibility, ensuring sustained activity.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Moderate

While mouse models indicate low oral acute toxicity (LD50 2000 mg/kg) and no mutagenic activity, specific safety assessments by CIR, SCCS, or FDA for cosmetic dermal use are currently unavailable. Due to its rich phenolic content, particularly carvacrol and thymol, there is a potential for skin irritation or sensitization, especially at higher concentrations or for individuals with sensitive skin.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Verdict

Optional

Coridothymus Capitatus Oil demonstrates promising antimicrobial and antioxidant benefits for targeted skincare; however, its moderate potential for irritation and lack of specific cosmetic safety assessments necessitate careful formulation and cautious use, particularly for sensitive skin types.

Related

Similar Ingredients

Finding similar ingredients…