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Moumoujus

CORIANDRUM SATIVUM LEAF/STEM JUICE.

Valuable / SKIN CONDITIONING - MISCELLANEOUS

Derived from the leaves and stems of the coriander plant, this botanical ingredient offers comprehensive skin benefits, including potent antioxidant and anti-aging properties. It actively protects against environmental stressors and supports skin's natural regeneration processes.

Summary

Antioxidant Anti-aging Photoprotective Anti-inflammatory Anti-allergic Antimicrobial Moisturizer Emollient Skin conditioning Antiseborrhoeic Masking

Science

Mechanism of Action

Coriandrum Sativum Leaf/Stem Juice functions through multiple pathways to enhance skin health. It acts as a powerful antioxidant by directly scavenging UVB-induced Reactive Oxygen Species (ROS) and boosting the skin's endogenous antioxidant defense systems, such as glutathione, superoxide dismutase, catalase, and Nrf2 expression. For anti-aging, it increases procollagen type I synthesis and reduces Matrix Metalloproteinase-1 (MMP-1) activity, which degrades collagen, thereby mitigating UVB-induced photoaging. The presence of fatty acids like oleic, linoleic, and palmitic acids contributes to its anti-inflammatory effects, while specific mechanisms involving the suppression of degranulation and Ca2+ concentration mediate its anti-allergic properties. Furthermore, it exhibits antimicrobial activity and helps fortify the skin barrier as a moisturizer and emollient.

Research

Clinical Evidence

High confidence
Effective range 0.01–1%
Optimal

N/A

Key findings

  1. 01 At 0.01% concentration, it significantly reduced Reactive Oxygen Species (ROS) levels by 43% and boosted procollagen type I production by up to 50% in human dermal fibroblasts exposed to UVB irradiation.
  2. 02 In an in-vivo study on photo-aged mouse skin, concentrations between 0.5% and 1% led to thinner epidermal layers, increased density of dermal collagen fibers, decreased levels of MMP-1, and elevated procollagen type I levels.
  3. 03 It protected human HaCaT keratinocytes from hydrogen peroxide-induced oxidative stress in a dose-dependent manner by enhancing glutathione levels, increasing the activity of superoxide dismutase and catalase, and promoting activated Nrf2 expression.
  4. 04 At concentrations of 0.1% or higher, it demonstrated a significant anti-allergic effect by inhibiting degranulation in RBL-2H3 cells without inducing cytotoxicity.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Not reviewed
Pregnancy
Caution
Sensitization risk Unknown

An aqueous extract of Coriandrum sativum has been reported to induce severe malformations during embryonic development and showed mutagenicity at high concentrations in Salmonella typhimurium strains, indicating it cannot be considered safe in these specific contexts. Further safety assessment for topical use, especially during pregnancy, is critical.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Coriandrum Sativum Leaf/Stem Juice is a valuable ingredient for its significant antioxidant, anti-aging, and soothing properties across various skin types, though its use requires careful consideration of concentration due to reported mutagenicity at high levels and specific contraindications during embryonic development.

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