Science
Mechanism of Action
This extract operates through multiple pathways to support skin health. Its high concentration of beneficial flavonoids and phenolic compounds enables robust antioxidant defense by scavenging free radicals. Furthermore, it modulates inflammatory responses by inhibiting the release of key proinflammatory cytokines such as TNF-α, IL-6, and IL-1β, thereby reducing skin discomfort. Preliminary in vitro research also suggests a capacity for cellular revitalization, specifically reversing neuronal apoptosis.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 An in vitro study demonstrated that at a concentration of 150 µg/ml, Coreopsis Tinctoria Flower Extract restored cell activity to 87.628% of control levels and notably reversed neuronal apoptosis.
- 02 In an in vivo mouse model, oral administration at 0.5 and 1.0 g/kg exhibited hepatoprotective effects, evidenced by a reduction in oxidative stress markers like malondialdehyde and nitric oxide, a decrease in proinflammatory cytokines (TNF-α, IL-1β), and an enhancement of endogenous antioxidant enzymes.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
The extract's solubility in water and hydroalcoholic solutions, such as ethanol/water mixtures commonly used for extraction, makes it versatile for diverse aqueous-based formulations.
Safety
Safety Profile
While the Cosmetic Ingredient Review (CIR) Expert Panel has not specifically assessed COREOPSIS TINCTORIA FLOWER EXTRACT, animal studies suggest its water-soluble components are non-toxic. SkinSAFE also categorizes similar extracts ('COREOPSIS TINCTORIA FLOWER LEAF STEM EXTRACT') as 'Irritant Free', indicating a favorable safety profile.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Coreopsis Tinctoria Flower Extract is a valuable botanical ingredient offering robust antioxidant and anti-inflammatory benefits suitable for all skin types, with a favorable safety profile.
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