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COPTIS JAPONICA RHIZOME EXTRACT.

Valuable CAS 223748-66-1 / ANTIMICROBIAL, SKIN CONDITIONING

Coptis Japonica Rhizome Extract, sourced from the Japanese goldthread plant, is a botanical ingredient rich in beneficial alkaloids such as berberine. It is recognized for its potent antioxidant, anti-inflammatory, and antimicrobial properties, making it a versatile asset for enhancing skin health and resilience.

Summary

Antioxidant Anti-inflammatory Antimicrobial Soothing Skin Barrier Support Moisture Retention Skin Regeneration Skin Tone Evening Anti-Acne

Science

Mechanism of Action

The mechanism of Coptis Japonica Rhizome Extract is rooted in its high concentration of active alkaloids, including berberine, coptisine, and palmatine. These compounds provide robust antioxidant activity, effectively neutralizing free radicals to combat signs of premature aging and support healthy collagen production for firmer, more radiant skin. Concurrently, its anti-inflammatory effects help to visibly diminish redness, soothe irritation, and aid in the skin's recovery from environmental stressors. The extract also exhibits antibacterial properties beneficial for managing acne and reducing breakouts. Additionally, it strengthens the skin's natural protective barrier, thereby reducing sensitivity, supporting optimal moisture retention, and promoting a more even and regenerated skin tone.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 A human patch test conducted on sensitive skin, utilizing a solubilized essence containing 2% Coptis Japonica extract, resulted in no stimulus reactions and a 0 stimulus figure score after 24 hours. This directly indicates its excellent safety and tolerability for sensitive skin types.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Ethanol is known to enhance the solubility and extraction efficiency of the beneficial alkaloids and other bioactive compounds within the rhizome. This ingredient is frequently formulated in water and butylene glycol bases, indicating good compatibility within common cosmetic systems.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

Coptis Japonica Extract generally possesses a favorable safety profile and is well-tolerated, as supported by an Environmental Working Group (EWG) Skin Deep rating of 'LOW' for various concerns. A 2% concentration was found to be non-irritating in a human patch test on sensitive skin. While occasional mild skin irritation, redness, or itching may occur in individuals with extremely sensitive or allergy-prone skin, a preliminary patch test is always advisable.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Coptis Japonica Rhizome Extract is a valuable botanical ingredient due to its multifaceted benefits, including robust antioxidant activity, anti-inflammatory effects, and barrier support, making it well-suited for a broad spectrum of skin types, notably sensitive skin.

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