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Moumoujus

COPRINUS COMATUS POWDER.

Valuable / ANTIOXIDANT

Coprinus comatus powder, derived from the Shaggy Mane mushroom, is a multifunctional skincare ingredient lauded for its potent antioxidant and soothing properties. It actively protects the skin from environmental stressors, calms irritation, and supports overall skin health, making it particularly beneficial for dry and sensitive complexions.

Summary

Antioxidant Soothing Skin-conditioning

Science

Mechanism of Action

This ingredient exerts its effects through a rich profile of bioactive compounds, including polysaccharides (notably beta-glucans), triterpenoids (like ergosterol), proteins, amino acids, nucleic acids, and essential minerals. These components collectively combat oxidative stress by neutralizing free radicals, thereby mitigating premature skin aging. Additionally, its inherent anti-inflammatory properties contribute to reducing skin redness and soothing irritation. The presence of polysaccharides also suggests immunomodulatory effects, while other compounds may enhance skin hydration, moisture retention, and potentially contribute to a more even skin tone by addressing hyperpigmentation.

Research

Clinical Evidence

Medium confidence
Effective range 0.1–8%
Optimal

N/A

Key findings

  1. 01 In vitro studies demonstrated significant antioxidant activity, with an ethanol extract achieving 63.4% activity at 1 mg/mL and a water extract reaching 65.6% at 5 mg/mL.
  2. 02 It effectively scavenged superoxide radicals with an IC50 of 1.03 mg/mL and hydroxyl radicals at an IC50 of 0.66 mg/mL.
  3. 03 DPPH radical scavenging activity exceeded 77.2% within a concentration range of 4-8 mg/mL.
  4. 04 At 1.0-2.0 mg/mL, it exhibited a strong inhibitory effect on microsomal liposome oxidation, with an inhibition rate surpassing 85%.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH 6 – 8
0 7 14

Stability

Optimal pH range for mycelial growth is 6-8, with pH 7 noted for highest mycelial dry weight, suggesting optimal stability and efficacy within this range for cosmetic formulations.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Moderate

While generally considered non-toxic, especially its polysaccharide components, it lacks specific CIR or SCCS safety reviews for cosmetic use. Notably, it has been observed to induce delayed-type skin reactions in individuals with existing atopic dermatitis or a predisposition to atopic conditions, necessitating caution for these skin types.

Your Skin

Skin Compatibility

No Normal
Yes Dry
No Oily
Yes Sensitive
Irritancy Medium
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Coprinus comatus powder is a valuable ingredient, offering robust antioxidant and soothing benefits, though careful formulation is advised for individuals with sensitive or atopic skin.

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