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COPPER TETRAPEPTIDE-52 DIMER.

Valuable / HAIR CONDITIONING, HAIR DYEING

COPPER TETRAPEPTIDE-52 DIMER is a signaling peptide that leverages copper to activate the skin's inherent repair mechanisms. It is designed to stimulate regeneration, enhance structural integrity, and visibly diminish wrinkles. This ingredient also provides antioxidant and anti-inflammatory benefits for comprehensive skin health.

Anti-aging Skin Regeneration Wound Healing Antioxidant Anti-inflammatory Collagen Synthesis Elastin Synthesis Hair Conditioning Hair Dyeing

Science

This dimeric copper peptide functions by signaling the skin to initiate its endogenous repair processes. It actively promotes the regeneration of mature skin cells, strengthening the dermal structure and contributing to a noticeable reduction in wrinkle depth. The ingredient stimulates the synthesis of vital proteins like collagen and elastin, enhances angiogenesis (blood vessel formation), and encourages the proliferation of skin stem cells. Furthermore, it demonstrates anti-inflammatory properties by neutralizing free radicals and suppressing inflammatory mediators, attracts repair cells to damaged areas, and boosts the production of metalloproteinases and various growth factors, all while supporting dermal fibroblast function and basal stem cell survival for improved skin appearance.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH 4 – 9
0 7 14

Stability

COPPER TETRAPEPTIDE-52 DIMER exhibits remarkable pH-adaptive stability, maintaining its structural integrity across a broad range from pH 4 to 9. This adaptability ensures performance in various skin conditions, from naturally acidic to more alkaline environments. Its dimeric structure also confers superior resistance to proteases compared to its monomeric counterparts, likely due to reduced enzyme access.

Conflicts

  • As with other potent copper peptides, it is generally recommended to alternate COPPER TETRAPEPTIDE-52 DIMER with other strong active ingredients, such as alpha hydroxy acids (AHAs), beta hydroxy acids (BHAs), and retinoids, rather than combining them in the same routine. This precaution aims to minimize potential interactions, over-exfoliation, or irritation.

Safety

CIR Status
Not reviewed
Sensitization risk Low

While a specific Cosmetic Ingredient Review (CIR) status is not documented, COPPER TETRAPEPTIDE-52 DIMER is listed by COSMILE Europe as an authorized substance under Annex III of the EC Cosmetics Regulation. This authorization follows a comprehensive assessment by the Scientific Committee on Consumer Safety (SCCS), indicating its safety for use under specified conditions within the European Union.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Valuable

COPPER TETRAPEPTIDE-52 DIMER is a valuable ingredient for its broad regenerative, anti-aging, and skin-repairing properties, supported by its stable formulation profile and EU safety assessment.


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