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COMMIPHORA SCHIMPERI GUM OIL.

Valuable CAS 89997-88-6 / PERFUMING

A potent botanical resin extract derived from the Schimperi Myrrh tree, valued for its concentrated terpenoid profile and historical use in wound healing. In precision skincare, it serves as a dual-action bioactive that simultaneously targets microbial imbalances and inflammatory pathways.

Antibacterial agent Anti-inflammatory Fragrance component Skin conditioning

Science

This gum oil operates through a multi-pathway approach: it exerts direct antibacterial pressure on Gram-positive pathogens like S. aureus by disrupting cellular membranes, while its volatile components modulate nitric oxide (NO) production in macrophages to effectively suppress cutaneous inflammatory responses.


Research

Medium confidence
Effective range 0.001–20%
Optimal

N/A

Key findings

  1. 01 Complete inhibition of Staphylococcus aureus was observed using a 200 mg/mL concentration of the gum-resin extract.
  2. 02 Significant anti-inflammatory activity demonstrated by the modulation of NO production in LPS-stimulated cells at concentrations of 10-20 µg/mL.

Transparency

Commonly dusted
Min. effective
0.1%
Red flag below
0.05%

Due to its potent aromatic profile and lack of broad clinical standardization, many brands include this at symbolic 'label' concentrations (below 0.1%) rather than the higher concentrations required for measurable antibacterial efficacy.


The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Highly sensitive to photo-oxidation and thermal degradation; microencapsulation is recommended to preserve the integrity of its volatile terpenoids.

Synergies

  • Commiphora Myrrha
  • Tocopherol
  • Antioxidant blends

Conflicts

  • Strong oxidizing agents

Safety

CIR Status
Not reviewed
Sensitization risk Moderate

While not formally classified as hazardous, its status as a fragrant essential oil poses a potential risk for contact dermatitis in sensitized individuals. Use caution in high-fragrance formulations.


Your Skin

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Valuable

A promising bioactive resin for addressing inflammatory and microbial skin concerns, though its use requires careful stabilization and consideration of its aromatic potency.


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