Science
Mechanism of Action
Colostrum Whey exerts its multifaceted effects through key growth factors, including insulin-like growth factor 1 (IGF-1), transforming growth factor beta (TGF-β), and epidermal growth factor (EGF). These stimulate fibroblast activity and collagen production, leading to improved skin elasticity and a reduction in visible wrinkles. The ingredient promotes robust cell proliferation, accelerates cellular turnover, precisely regulates the extracellular matrix, and influences collagen organization. It is rich in prebiotics, potent antioxidants, anti-inflammatory compounds, and regenerative peptides. Lactoferrin, a prominent component, offers anti-inflammatory and antimicrobial properties, while immunoglobulins provide essential immune protection. Furthermore, Colostrum Whey upregulates aquaporin-3 (AQP3) protein, significantly facilitating water and glycerol transport for enhanced skin hydration. Its components collectively strengthen the skin barrier and deliver vital micronutrients, including vitamins (A, B, C, E) and minerals (Zn, Cu).
Research
Clinical Evidence
High confidenceN/A
Key findings
- 01 A cream containing 15% sheep colostrum demonstrated significant improvements in skin hydration, regeneration, tone, and softness. It also reduced redness and skin hypersensitivity, decreased sebum production in oily skin, and effectively improved or prevented acne lesions.
- 02 A 20% horse colostrum emulsion, when applied twice daily for 30 days, showed superior softening, moisturizing, soothing, and anti-inflammatory effects compared to common emulsions in patients with moderate atopic dermatitis, leading to reduced erythema and pruritus without adverse reactions.
- 03 In an in vitro scratch wound assay, bovine colostrum at 5% and 10% significantly promoted human keratinocyte migration, enhanced cell growth, and facilitated re-epithelialization at the wound site.
- 04 In an in vitro study, sheep colostrum stimulated normal fibroblast proliferation by 191.2% after 24 hours and 222.2% after 48 hours, highlighting its regenerative potential.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Heat treatment can cause denaturation or aggregation of proteins, potentially diminishing the activity of bioactive compounds. Colostrum whey protein nanoparticles have exhibited stability for up to 1 month when stored at 25°C. Whey proteins generally maintain solubility across a broad pH range.
Safety
Safety Profile
The CIR Expert Panel concluded in April 2017 that 16 bovine milk proteins and derivatives, including Whey Protein (a primary component of colostrum whey), are safe under current practices of use and concentration. No specific SCCS or FDA status for 'Colostrum Whey' was identified, but its components are considered safe.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Colostrum Whey is a valuable and highly versatile ingredient, offering comprehensive benefits for skin health, including anti-aging, intense hydration, barrier repair, and soothing effects across diverse skin types.
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