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CODONOPSIS LANCEOLATA EXTRACT.

Valuable CAS - / ANTIOXIDANT, ASTRINGENT, SKIN CONDITIONING

A nutrient-dense botanical extract derived from the root of the Deodeok plant, prized in precision skincare for its high concentration of saponins and polyphenols. It serves as a multi-functional restorative agent that balances hydration while providing robust protection against environmental oxidative stress.

Antioxidant Skin-soothing Humectant Anti-inflammatory

Science

This extract operates through a dual-action pathway of cytokine modulation and free-radical neutralization. It inhibits the IKK/NF-κB signaling cascade to suppress inflammatory responses in macrophages, while its rich phytochemical profile—including triterpenes and alkaloids—scavenges reactive oxygen species (ROS) and strengthens the skin's structural integrity.


Research

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Clinical evaluation of fermented extract demonstrated a 15% increase in corneal layer hydration and a significant 131% improvement in surface lipid levels.

Transparency

Commonly dusted
Min. effective
1%
Red flag below
0.1%

Due to its complex phytochemical profile, this extract is often included at sub-clinical levels (<0.1%) for label-claims. To achieve the recorded anti-inflammatory and moisturizing benefits, it should be present in concentrations reflecting the clinical fermentation studies.


The Formula

Solubility
Both
Optimal pH 2.98 – 6.25
0 7 14

Stability

Demonstrates excellent stability for 60+ days within a weakly acidic environment. It is highly versatile for various galenic forms including emulsions and aqueous essences.

Synergies

  • Antioxidants
  • Humectants
  • Soothing agents

Safety

CIR Status
Not reviewed
Pregnancy
Safe
Sensitization risk Low

While lacking a formal CIR monograph, human clinical trials and subchronic toxicity data indicate a high safety profile; it has a long history of safe use in both topical and ingestible forms in East Asia.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Valuable

A potent botanical restorative that excels at enhancing skin barrier hydration and suppressing inflammatory markers.


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