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CODIUM FRAGILE/ENTEROMORPHA COMPRESSA LEAF EXTRACT.

Valuable / HUMECTANT, SKIN CONDITIONING

A synergistic marine complex derived from green macroalgae that provides multi-depth epidermal hydration and potent anti-inflammatory protection. This botanical duo excels at maintaining osmotic balance while shielding the skin against oxidative stress and structural degradation.

Humectant Anti-inflammatory Antioxidant Barrier Repair Skin Conditioning

Science

This extract functions as a biological hydrator and barrier fortifier. Codium fragile optimizes water transport across epidermal layers and stimulates collagen synthesis, while Enteromorpha compressa provides essential electrolytes and polysaccharides to maintain homeostasis. Together, they inhibit inflammatory mediators such as nitric oxide (NO) and prostaglandin E2 (PGE2) and neutralize free radicals with an efficacy comparable to synthetic antioxidants like BHT.


Research

High confidence
Effective range 0.005–5%
Optimal

5%

Key findings

  1. 01 Clinical application of a 5% Codium extract demonstrated an immediate 100% increase in moisture levels, maintaining significant elevation for 3+ hours and achieving a 20% improvement over controls after 7 days of bi-daily use.
  2. 02 In vitro testing of Enteromorpha compressa showed antioxidant inhibition rates between 82.8% and 95.7% (DPPH method) at concentrations of 100-200 μg/mL.
  3. 03 Codium fragile extract at 50-200 μg/mL significantly suppressed inflammatory responses in RAW264.7 cells by inhibiting LPS-induced secretion of NO and PGE2.

Transparency

Commonly dusted
Min. effective
1%
Red flag below
0.1%

While often included at minute 'claim' levels for its exotic marine profile, clinical data suggests significant hydration benefits require concentrations closer to 5%, and anti-inflammatory/antioxidant protection starts at levels above 100 μg/mL.


The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Heat sensitive; the extract should be incorporated into the cooling phase of formulations at temperatures below 40°C to preserve bioactivity.

Synergies

  • Hyaluronic Acid
  • Glycerin
  • Niacinamide

Safety

CIR Status
Insufficient data
Pregnancy
Safe
Sensitization risk Low

Generally well-tolerated as a botanical extract. While formal CIR 'safe as used' conclusions for this specific combination are pending, individual components are widely used in skincare without systemic safety concerns.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A high-performance marine botanical that bridges the gap between simple humectants and advanced anti-inflammatory actives, particularly effective for moisture retention and barrier support.


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