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Moumoujus

COCOBUTYRAMIDO HYDROXYSULTAINE.

Valuable CAS 2041102-83-2 / CLEANSING, SOLVENT, SURFACTANT - CLEANSING, SURFACTANT - EMULSIFYING, SURFACTANT - FOAM BOOSTING, VISCOSITY CONTROLLING

COCOBUTYRAMIDO HYDROXYSULTAINE, often referred to as Cocamidopropyl Hydroxysultaine, is a coconut-derived amphoteric surfactant meticulously engineered for gentle yet effective cleansing. It functions to stabilize surfactant micelles, significantly reducing irritation potential while enhancing foam quality and stability. This versatile ingredient also offers conditioning benefits, leaving skin feeling soft and hydrated.

Summary

Antistatic Cleansing Foam Boosting Hair Conditioning Skin Conditioning Surfactant Viscosity Controlling

Science

Mechanism of Action

As an amphoteric surfactant, COCOBUTYRAMIDO HYDROXYSULTAINE lowers the surface tension, aiding in effective cleansing. Its key mechanism involves stabilizing micelles formed by anionic surfactants, crucial for preventing irritating surfactant monomers from penetrating the stratum corneum and disrupting the skin's lipid barrier. This action significantly enhances formulation mildness. Furthermore, it acts as a conditioning agent, forming a thin protective layer that helps to prevent moisture loss, contributing to smoother, more radiant skin.

Research

Clinical Evidence

High confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 When integrated into cleansers, COCOBUTYRAMIDO HYDROXYSULTAINE facilitates the formation of more stable micelles with anionic surfactants. This reduces the concentration of irritating surfactant monomers, thereby minimizing penetration into the stratum corneum and preserving skin barrier integrity, resulting in lower irritation and enhanced mildness.
  2. 02 Clinical observations demonstrate that this ingredient enhances foaming characteristics, producing a rich, creamy lather. This allows for potentially lower overall surfactant concentrations in formulations, contributing to a soft, moist, and hydrated skin feel without stripping essential moisture.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH 4.5 – 7.5
0 7 14

Stability

COCOBUTYRAMIDO HYDROXYSULTAINE exhibits robust stability across a wide pH spectrum, encompassing both acidic and alkaline conditions. It can also contribute to improved low-temperature stability in detergent systems.

Synergies

  • Enhances mildness and foam characteristics when combined with anionic surfactants.

Conflicts

  • Avoid use in cosmetic products where N-nitroso compounds can potentially form; manufacturers are advised to strictly limit N-nitrosatable impurities.

Safety

Safety Profile

CIR Status
Safe as used
Max tested
11.5%
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has assessed COCOBUTYRAMIDO HYDROXYSULTAINE (as Cocamidopropyl Hydroxysultaine) and deemed it safe for cosmetic use. The maximum reported use concentration is 11.5% in rinse-off products and up to 0.05% in leave-on products. While animal studies indicate a low risk of skin irritation (not irritating at 41.5% in rabbits) and sensitization (not sensitizing at 42% in guinea pigs or 2.5% in humans), some human testing has reported slight-to-moderate skin irritation. At high concentrations (up to 41.5%), it was predicted to be a severe ocular irritant. Regulatory bodies, including the FDA and EU Cosmetics Regulation, have affirmed its safety within specified concentration limits. It is considered non-comedogenic and biodegradable. A critical recommendation from CIR is to avoid its use in products where N-nitroso compounds can be formed, mandating manufacturers to implement cGMPs to control N-nitrosatable impurities.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

COCOBUTYRAMIDO HYDROXYSULTAINE is a valuable amphoteric surfactant for Moumoujus, offering superior mild cleansing, enhanced foam characteristics, and conditioning benefits, making it particularly well-suited for formulations targeting sensitive or dry skin.

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