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CLADOSIPHON NOVAE-CALEDONIAE POLYSACCHARIDE.

Valuable CAS - / HUMECTANT, SKIN PROTECTING

A high-purity marine polysaccharide derived from New Caledonian brown algae, prized for its exceptional moisture-binding and bioactive properties. This botanical complex acts as a biological shield, offering multi-dimensional support for skin barrier recovery and pigmentation control.

Antioxidant Humectant Skin Brightening Anti-inflammatory Barrier Repair

Science

This polysaccharide functions as a potent antioxidant by neutralizing DPPH free radicals and reducing reactive oxygen species (ROS) induced by UVB exposure. It regulates melanogenesis by inhibiting tyrosinase activity and exerts immunomodulatory effects through the downregulation of inflammatory cytokines (such as IL-4 and IL-33) while promoting TGF-β1 to accelerate tissue repair and improve skin elasticity.


Research

High confidence
Effective range 0.1–500%
Optimal

N/A

Key findings

  1. 01 In vitro testing demonstrated an 89% DPPH free radical scavenging rate at a concentration of 500µg/mL.
  2. 02 Comparative studies showed tyrosinase inhibition reaching up to 49%, performing at levels comparable to the brightening agent arbutin.
  3. 03 Bio-active assays indicate significant reductions in syncytia formation (66%) and suppression of atopic-associated cytokines in animal models.

Transparency

Commonly dusted
Min. effective
0.01%
Red flag below
0.05%

Due to its potency in small concentrations (as low as 0.1 μg/mL in some antiviral/cellular studies), it is often included at negligible levels purely for label claims. Effective skin barrier modulation typically requires higher inclusion rates.


The Formula

Solubility
Water
Optimal pH 6 – 8
0 7 14

Stability

Maintains structural integrity and gelling capacity most effectively in near-neutral environments; sensitive to extreme acidification.

Synergies

  • Hyaluronic Acid
  • Niacinamide
  • Peptides

Safety

CIR Status
Insufficient data
Pregnancy
Safe
Sensitization risk Low

While the 2019 CIR report requested more data, subsequent 2022 reviews and EWG assessments indicate low concerns regarding immunotoxicity or reproductive health.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A high-performance marine bio-active that bridges the gap between deep hydration and advanced inflammatory regulation.


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