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Moumoujus

CITRUS UNSHIU/SINENSIS/RETICULATA FRUIT EXTRACT.

Valuable CAS - / SKIN CONDITIONING

A multi-faceted botanical complex derived from Satsuma, Sweet Orange, and Tangerine fruits, engineered to provide comprehensive oxidative protection and skin tone regulation. This bio-active blend leverages high concentrations of citrus flavonoids and Vitamin C to reinforce the skin barrier while actively mitigating inflammatory signaling.

Summary

Antioxidant Skin Brightening Anti-inflammatory Humectant TRPV1 Antagonist

Science

Mechanism of Action

This extract operates through several biological pathways: it inhibits tyrosinase activity to modulate melanin production and brighten hyperpigmentation, while simultaneously suppressing NF-κB and MAPK signaling to quench inflammation. Additionally, it acts as a TRPV1 antagonist, which effectively raises the skin's tolerance threshold to external irritants, and stimulates hyaluronic acid and collagen synthesis to improve dermal elasticity.

Research

Clinical Evidence

High confidence
Effective range 0.25–4%
Optimal

2.5%

Key findings

  1. 01 Inhibition of TRPV1 activation observed at 1-4% concentrations, significantly reducing neurogenic discomfort and enhancing tolerance in sensitive skin.
  2. 02 Immature fruit extracts demonstrated significant anti-inflammatory effects by inhibiting nitric oxide production and pro-inflammatory cytokines below 250 µg/mL.
  3. 03 Topical application at 0.25% was sufficient to suppress TRPV1 protein expression in vitro.

Transparency

Dusting Analysis

Commonly dusted
Min. effective
0.5%
Red flag below
0.1%

Due to its botanical nature, this extract is frequently used at trace levels (below 0.1%) for 'label claims' rather than efficacy. To achieve the documented TRPV1 modulation and anti-inflammatory benefits, concentrations should ideally exceed 0.25-1%.

The Formula

Formulation

Solubility
Both
Optimal pH 3.5 – 6
0 7 14

Stability

Contains both water-soluble phenolics and oil-soluble essential oil components; stability is highest in slightly acidic environments. Extract integrity is sensitive to prolonged light and air exposure.

Synergies

  • Niacinamide
  • Hyaluronic Acid
  • Vitamin E
  • Broad-spectrum SPF

Conflicts

  • High-heat processing
  • Strong Oxidizers
  • Excessive concentrations of other volatile citrus oils

Safety

Safety Profile

CIR Status
Safe with restrictions
Pregnancy
Safe
Sensitization risk Moderate

Safe for cosmetic use provided that leave-on formulations limit 5-methoxypsoralen (5-MOP) to 15 ppm to avoid phototoxicity. Manufacturers must ensure the final formula is non-sensitizing despite the presence of natural limonene or citral.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

A high-performance botanical complex that balances brightening efficacy with unique neuro-soothing properties for sensitive skin.

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