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Moumoujus

CITRUS UNSHIU FRUIT JUICE.

Valuable CAS 98106-71-9 / HUMECTANT, SKIN CONDITIONING

Derived from the Satsuma mandarin, Citrus unshiu fruit juice is a multi-functional ingredient known for its capacity to condition, brighten, and soothe the skin. Rich in beneficial compounds, it offers antioxidant protection and contributes to improved skin hydration and reduced inflammatory responses.

Summary

Skin conditioning Antioxidant Skin brightening Anti-inflammatory Humectant Anti-aging Anti-allergic Skin protecting

Science

Mechanism of Action

This ingredient functions through several biological pathways: it inhibits key inflammatory mediators like nitric oxide, TNF-α, and IL-6, along with suppressing iNOS, COX-2, NF-κB, and MAPK signaling. It also reduces inflammatory chemokines (TARC, MDC) by blocking STAT1 phosphorylation. For anti-aging and hydration, it promotes hyaluronic acid synthesis. Its high content of flavonoids and carotenoids provides antioxidant defense against free radicals and UV damage. Additionally, it helps brighten skin by inhibiting tyrosinase, an enzyme crucial for melanin production.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

No data available in the provided research to suggest this ingredient is commonly 'dusted' in formulations.

The Formula

Formulation

Solubility
Water
Optimal pH 3 – 4.2
0 7 14

Stability

Optimal stability is typically maintained within an acidic pH range of 3.0 to 4.2, aligning with its natural pH (3.5-4.0), which helps limit microbial proliferation. Stability can be influenced by factors such as fruit maturity, cultivar, harvesting methods, and post-processing/storage conditions.

Conflicts

  • Volatile fragrance chemicals inherently present in citrus extracts can potentially cause skin aggravation, necessitating careful formulation to ensure non-irritating and non-sensitizing properties.
  • Ingredients known to be sensitive or unstable in highly acidic environments (pH below 4.5, particularly below 3.5).

Safety

Safety Profile

CIR Status
Safe with restrictions
Sensitization risk Moderate

The CIR Expert Panel deems citrus fruit-derived ingredients, including Citrus unshiu fruit juice, safe for both rinse-off and leave-on cosmetic applications, provided they are formulated to be non-sensitizing and non-irritating. A critical restriction for leave-on products specifies a maximum content of 0.0015% (15 ppm) for the phototoxic compound 5-methoxypsoralen (5-MOP). No skin irritation was observed in studies of citrus fruit derivatives when properly formulated. The U.S. FDA recognizes Citrus fruits as Generally Recognized As Safe (GRAS) for direct food consumption.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Citrus unshiu fruit juice is a valuable ingredient, offering proven anti-inflammatory, antioxidant, brightening, and hydrating benefits, provided formulations adhere to safety guidelines regarding 5-MOP content and potential irritancy.

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