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Moumoujus

CITRUS TANGERINA EXTRACT.

Valuable CAS 223748-44-5 / TONIC

Citrus Tangerina Extract, derived from *Citrus reticulata*, is a multi-functional ingredient known for its potent antioxidant capabilities. It actively reduces skin irritation and sensitivity by modulating TRPV1 pathways, while also contributing to skin brightening and improved elasticity.

Summary

Antioxidant Skin Brightening Anti-inflammatory Exfoliant Antibacterial Astringent Collagen Stimulating Hydrating Wound Healing

Science

Mechanism of Action

This extract combats oxidative stress through its rich composition of Vitamin C, flavonoids, and polyphenols. It stimulates collagen synthesis, enhancing skin firmness, and provides gentle exfoliation via natural citric acid to refine pores. Crucially for sensitive skin, it modulates TRPV1 function, inhibiting activation at 1-4% and suppressing protein expression at 0.25%, thereby reducing irritation. Further benefits include mild antibacterial action, astringent properties for oily skin, and inhibition of melanin generation for a more even tone.

Research

Clinical Evidence

Medium confidence
Effective range 0.25–4%
Optimal

1%

Key findings

  1. 01 Inhibited TRPV1 activation, providing instant relief from lactic acid-induced skin discomfort and enhancing skin tolerance after 7 days of continuous use.
  2. 02 Suppressed TRPV1 protein expression.
  3. 03 Showed tyrosinase inhibition, though classified as a weak whitening agent compared to kojic acid.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Tangerine juice pH values typically range from 3.38-3.41, suggesting stability within an acidic environment. The extract can be obtained via water or organic solvent extraction.

Conflicts

  • Formulators must adhere to the CIR restriction for leave-on products, ensuring 5-methoxypsoralen (5-MOP) content does not exceed 0.0015% (15 ppm).
  • High concentrations of essential oil components may cause concern for highly sensitive individuals due to potential fragrance allergens or phototoxic compounds.

Safety

Safety Profile

CIR Status
Safe with restrictions
Max tested
3.06%
Sensitization risk Low

The CIR Expert Panel concluded that Citrus peel-derived ingredients, including Citrus Reticulata (Tangerine) Peel Extract, are safe in cosmetic products when formulated to be non-sensitizing and non-irritating, specifically limiting 5-methoxypsoralen (5-MOP) to 0.0015% (15 ppm) in leave-on products. In vitro tests observed no irritation at 3.0% and transient irritation at 3.06% that resolved within 24 hours. The FDA recognizes Tangerine, Extract as generally safe (GRAS) for food use.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Citrus Tangerina Extract is a valuable ingredient for its demonstrated efficacy in antioxidant protection, skin brightening, and reducing sensitivity, provided precise formulation adheres to CIR safety guidelines, especially regarding 5-MOP content.

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