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Moumoujus

CITRUS GRANDIS PEEL/SEED EXTRACT.

Valuable / ANTIMICROBIAL

This botanical extract, derived from the peel and seeds of grapefruit (Citrus grandis), offers a powerful blend of antioxidant, antimicrobial, and exfoliating properties. It is engineered to protect the skin from environmental stressors, purify the complexion, and promote cellular renewal for a visibly smoother and brighter appearance.

Summary

Antimicrobial/Antibacterial Antioxidant Astringent Perfuming Skin-Conditioning Soothing

Science

Mechanism of Action

Citrus Grandis Peel/Seed Extract functions as a potent antioxidant, primarily due to its rich composition of vitamin C, flavonoids, and various polyphenols, which collectively neutralize free radicals and mitigate oxidative stress on skin cells. It exhibits intrinsic antimicrobial, antibacterial, and antifungal properties, aiding in the control of skin microorganisms and offering benefits for acne-prone skin. Furthermore, its astringent qualities help to visibly refine pores and regulate excess sebum production. The presence of naturally occurring alpha hydroxy acids (AHAs) and citric acid supports gentle exfoliation and accelerates cell renewal, contributing to a refined skin texture and enhanced radiance.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Crude dichloromethane extracts (25-100%) from pomelo albedo demonstrated significant antimicrobial effects against Colletotrichum gloeosporioides in an in vitro study.
  2. 02 An ethanolic peel extract exhibited strong antioxidant potential in an in vitro DPPH radical scavenging assay, with an IC50 of 0.532 ± 0.02 mg/mL.
  3. 03 Grapefruit peel extract showed notable DPPH radical scavenging activity in an in vitro antioxidant study within concentrations of 100-1000 µg/mL.
  4. 04 An inhibitory effect against α-glucosidase was observed in vitro with grapefruit peel extract at EC50 values ranging from 80-120 µg/mL.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH 2 – 3.5
0 7 14

Stability

The extract maintains optimal stability within an acidic pH range of 2.0 to 3.5.

Conflicts

  • Carbomer
  • Surfactants

Safety

Safety Profile

CIR Status
Safe with restrictions
Max tested
2%
Sensitization risk Moderate

The CIR Expert Panel has deemed Citrus Grandis Peel/Seed Extract safe under current practices, provided it is formulated to be non-irritating and non-sensitizing. The maximum reported concentration for related grapefruit seed extracts in face and neck formulations is 2%. This ingredient is also a restricted antimicrobial agent (II/358) under the European Cosmetics Regulation 1223/2009. Due to naturally occurring furanocoumarins, there is a moderate risk of mild skin irritation, allergic reactions, and photosensitivity, particularly in individuals with sensitive skin. A patch test is recommended, and its use is best suited for evening routines or in conjunction with a broad-spectrum sunscreen. Formulators must also ensure the absence of potentially toxic compounds like benzalkonium and benzethonium, which have been reported in some commercial grapefruit seed extracts.

Your Skin

Skin Compatibility

Yes Normal
No Dry
Yes Oily
No Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Citrus Grandis Peel/Seed Extract is a valuable, multi-functional ingredient providing significant antioxidant, antimicrobial, and mild exfoliating benefits, which requires careful formulation and consumer guidance due to potential photosensitivity and irritation risks.

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